Glucose tolerance depends on a complex interaction between a variety of different factors, including peripheral insulin sensitivity (SI), and pancreatic ß-cell responsiveness in the first phase (F1) and second phase (F2). These parameters are severely deranged in liver cirrhosis.[1]In order to clarify the differential impact of Cyclosporin A (CsA) versus Tacrolimus (FK) on these single factors in liver grafted patients, we investigated glucose tolerance using a modeling technique.

Effect of CsA versus FK 506 on insulin sensitivity and insulin response using a modeling technique.

TOFFOLO, GIANNA MARIA;COBELLI, CLAUDIO;
1998

Abstract

Glucose tolerance depends on a complex interaction between a variety of different factors, including peripheral insulin sensitivity (SI), and pancreatic ß-cell responsiveness in the first phase (F1) and second phase (F2). These parameters are severely deranged in liver cirrhosis.[1]In order to clarify the differential impact of Cyclosporin A (CsA) versus Tacrolimus (FK) on these single factors in liver grafted patients, we investigated glucose tolerance using a modeling technique.
1998
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11577/2508588
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