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EnglishAmong variuos furocoumarins studied , RBC hemolysis was significantly induced only by Psoralen and 3-CPS, although at higher concentrations than those used for photochemotherapeutic experiments. By pre-irradiating the compounds in methanol, and adding the solution to the RBC, damage on the cell membrane (hemolysis) was observed in various compounds, thus indicating a role of photoproducts in this toxic process.
| Titolo: | DARK AND PHOTOHEMOLYSIS OF ERYTHROCYTES BY FUROCOUMARINS |
| Autori: | |
| Data di pubblicazione: | 1988 |
| Rivista: | |
| Abstract: | Among variuos furocoumarins studied , RBC hemolysis was significantly induced only by Psoralen and 3-CPS, although at higher concentrations than those used for photochemotherapeutic experiments. By pre-irradiating the compounds in methanol, and adding the solution to the RBC, damage on the cell membrane (hemolysis) was observed in various compounds, thus indicating a role of photoproducts in this toxic process. |
| Handle: | http://hdl.handle.net/11577/2515337 |
| Appare nelle tipologie: | 01.01 - Articolo in rivista |
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