Some biochemical and histological findings in skeletal muscle tissue, obtained by needle biopsy from 22 patients with decompensated cirrhosis of the liver, are presented. Furthermore, the correlations between muscle composition analyses and electrolyte or acid-base balance are examined. Muscle analyses showed increased water, sodium, and chloride content; decreased potassium, magnesium, and protein nitrogen concentrations. No conclusive evidence of 'true' potassium depletion was found. However, a decrease in muscle potassium content was associated with extracellular metabolic alkalosis. Edema, nucleosis, and atrophy were the most common histological findings. They were in close agreement with the biochemical results of overhydration and decreased protein nitrogen content in muscle tissue. © 1971 Informa UK Ltd.
MUSCLE BIOPSY STUDIES IN LIVER CIRRHOSIS
D'ANGELO, ANGELA;
1971
Abstract
Some biochemical and histological findings in skeletal muscle tissue, obtained by needle biopsy from 22 patients with decompensated cirrhosis of the liver, are presented. Furthermore, the correlations between muscle composition analyses and electrolyte or acid-base balance are examined. Muscle analyses showed increased water, sodium, and chloride content; decreased potassium, magnesium, and protein nitrogen concentrations. No conclusive evidence of 'true' potassium depletion was found. However, a decrease in muscle potassium content was associated with extracellular metabolic alkalosis. Edema, nucleosis, and atrophy were the most common histological findings. They were in close agreement with the biochemical results of overhydration and decreased protein nitrogen content in muscle tissue. © 1971 Informa UK Ltd.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
