The X-ray diffraction structures of three N(alpha)-protected, C(alpha)-activated MeAib derivatives are reported. They are Tos-MeAib-Cl, Tos-MeAib-N3 and Tos-MeAib-O-Piv. The geometry and conformation of these classical carboxyl activating groups, which have been characterized at atomic resolution for the first time, are discussed.

Linear Oligopeptides .292. 1st Characterization At Atomic-resolution of the C-activating Groups In A Peptide-synthesis Acid Chloride, Acid Azide and Carboxylic Carboxylic Mixed Anhydride

FORMAGGIO, FERNANDO;TONIOLO, CLAUDIO
1993

Abstract

The X-ray diffraction structures of three N(alpha)-protected, C(alpha)-activated MeAib derivatives are reported. They are Tos-MeAib-Cl, Tos-MeAib-N3 and Tos-MeAib-O-Piv. The geometry and conformation of these classical carboxyl activating groups, which have been characterized at atomic resolution for the first time, are discussed.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11577/2523468
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