This study suggests that, at least at a preliminary level, it is possible to correlate the antimetastatic, antitumor and mutagenic properties of aryl- and heteroaryltriazenes with their EI behavior. This finding may have some potential towards the definition of a screening paradigm in which the first selection step is based on mass spectrometry followed by in vitro or in vivo biological assays.
Correlation of the antimetastatic properties of aryltriazenes with their electron impact ionization mass spectrometry
FAVRETTO, DONATA;
1997
Abstract
This study suggests that, at least at a preliminary level, it is possible to correlate the antimetastatic, antitumor and mutagenic properties of aryl- and heteroaryltriazenes with their EI behavior. This finding may have some potential towards the definition of a screening paradigm in which the first selection step is based on mass spectrometry followed by in vitro or in vivo biological assays.
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