Plasma leptin and energy expenditure during prolonged, moderate intensity, treadmill exercise.

Zaccaria, Marco; Ermolao, Andrea; Brugin, Erica; Bergamin, Marco

doi:10.3275/8656

Plasma leptin and energy expenditure during prolonged, moderate intensity, treadmill exercise.

ZACCARIA, MARCO;ERMOLAO, ANDREA;BRUGIN, ERICA;BERGAMIN, MARCO

2013

Scheda breve

Scheda completa

Scheda completa (DC)

	Anno
	
				2013
			
	Formato
	
				STAMPA
			
	Lingua/e pubblicazione
	
				Inglese
			
	Rivista su cui è pubblicata l'opera
	
				JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
			
	N° Volume
	
				36
			
	Serie (fascicolo)
	
				6
			
	Da pagina
	
				396
			
	A pagina
	
				401
			
	Totale pagine
	
				6
			
	Nome Editore
	
				Editrice Kurtis
			
	Diffusione
	
				Internazionale
			
	Referee
	
				Esperti anonimi
			
	Rivista indicizzata su WOS
	
				sì
			
	Codice DOI
	
				https://dx.doi.org/10.3275/8656
			
	Codice WOS
	
				WOS:000330269700007
			
	Codice Scopus
	
				2-s2.0-84881430859
			
	Codice OpenAlex
	
				W1536538783
			
	Categoria ISI-CRUI
	
				The Endocrinology, Metabolism & Nutrition category is concerned with resources on the growth and regulation of the human body. Coverage focuses on disorders associated with endocrine glands such as diabetes, osteoporosis, and obesity. Nutrition resources focus on topics such as diagnosis, treatment, and management of nutritional and metabolic disorders. Reproductive endocrinology is excluded and is placed in the Reproductive Medicine category.
			
	Note (altre informazioni)
	
				BACKGROUND: Current literature shows conflicting results regarding the possible direct role of exercise on leptin concentrations, mainly because of a
non-homogeneous level of energy expenditure (EE) and the lack of standardization of energy balance. AIM: The aim of the study was to evaluate the effect of exercise duration and its corresponding EE on leptin levels, during prolonged treadmill exercise, in a well-controlled laboratory setting.
MATERIALS AND METHODS: Seven young trained males underwent a 4-h treadmill exercise. The starting intensity was set at 65% of maximal oxygen consumption. At the start of the test and throughout the exercise, venous blood samples were
drawn for the assays of leptin, glucose, free fatty acids (FFA), cortisol,
epinephrine (E) and norepinephrine (NE). Hourly and total EE was monitored with gas analysis.
RESULTS: Plasma leptin levels decreased from 1.10±0.15 to 0.85±0.26 μg/l (p<0.01)
at the end of the exercise, reaching a significant reduction already after the
second hour. FFA and cortisol showed a progressive significant increase, while
glucose did not significantly change throughout the test. Plasma E and NE
significantly increased at all sampling times compared to basal values (48.1±30.3
to 352.3±187.7 pg/ml, p<0.001 and 238.1±118.9 to 1798.7±413.5 pg/ml, p<0.001).
The randomeffects model for panel data analysis showed negative correlation
between leptin, NE and the values of progressive EE (r2=0.745, p<0.05).
CONCLUSIONS: Our data demonstrate that, during a prolonged moderate intensity exercise, leptin decrease is significantly related to the total EE. Further, NE concentrations seem to play an important role in the inhibition of leptin secretion.
			
	Nazionalità Autore/i
	
				ITALIA
			
	Fulltext
	
				none
			
	Tutti gli autori
	
						Zaccaria, Marco; Ermolao, Andrea; Brugin, Erica; Bergamin, Marco
					
	Tipologia
	
				01 CONTRIBUTO IN RIVISTA::01.01 - Articolo in rivista
			
	Tipologia
	
				info:eu-repo/semantics/article
			
	Numero autori
	
				4
			
	Tipologia sito docente
	
				262
			
	Appare nelle tipologie:
	
				01.01 - Articolo in rivista