Objectives: Sex hormones strongly influence skin physiology and evidences suggest wound healing as well. Estrogens establish a prohealing setting, and androgens play an antagonist role. Methods and Results:We present the case of a young woman in whom pregnancy with its associated hormonal shifts allowed the spontaneous healing of a chronic wound on the left leg with bone exposure, which had followed a car accident and had resisted medical and surgical treatments for 5 years. Discussion: Systemic or topical estrogens may offer alternative options in the therapy of chronic wounds, in particular in the elderly adults who have physiologically reduced estrogens levels.
Therapeutic effects of pregnancy on a chronic skin ulcer.
LANCEROTTO, LAURA;BASSETTO, FRANCO;VINDIGNI, VINCENZO
2013
Abstract
Objectives: Sex hormones strongly influence skin physiology and evidences suggest wound healing as well. Estrogens establish a prohealing setting, and androgens play an antagonist role. Methods and Results:We present the case of a young woman in whom pregnancy with its associated hormonal shifts allowed the spontaneous healing of a chronic wound on the left leg with bone exposure, which had followed a car accident and had resisted medical and surgical treatments for 5 years. Discussion: Systemic or topical estrogens may offer alternative options in the therapy of chronic wounds, in particular in the elderly adults who have physiologically reduced estrogens levels.Pubblicazioni consigliate
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