Dermorphin structure-activity relationships toward μ and δ opioid receptors were investigated using a series of synthetic peptides, in which the aromatic residues at positions 1 or/and 3 of the N-terminal tetrapeptide analogue H-Tyr-D-Arg-Phe-β-Ala-NH2 were replaced by unnatural or constrained amino acids.

Synthesis, conformational and pharmacological studies on dermorphin N-terminal tetrapeptide analogues

CIMA, LORENZO;GIUSTI, PIETRO;
1998

Abstract

Dermorphin structure-activity relationships toward μ and δ opioid receptors were investigated using a series of synthetic peptides, in which the aromatic residues at positions 1 or/and 3 of the N-terminal tetrapeptide analogue H-Tyr-D-Arg-Phe-β-Ala-NH2 were replaced by unnatural or constrained amino acids.
1998
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11577/2990705
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