The biological activity of some pyrrolocoumarin derivatives has been studied after UVA irradiation and in the dark in Ehrlich ascites tumor cells: only one compound seemed to be able to inhibit DNA synthesis by UVA irradiation with ID50 similar to that od the reference 8-MOP. However this compound appeared to be capable of interfering with DNA synthesis also in the dark.
Photobiological activity of some pyrrolocoumarin derivatives
CHILIN, ADRIANA;
1989
Abstract
The biological activity of some pyrrolocoumarin derivatives has been studied after UVA irradiation and in the dark in Ehrlich ascites tumor cells: only one compound seemed to be able to inhibit DNA synthesis by UVA irradiation with ID50 similar to that od the reference 8-MOP. However this compound appeared to be capable of interfering with DNA synthesis also in the dark.
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