No established therapies for patients with hepatocellular carcinoma (HCC) and progression on first-line sorafenib treatment currently exist. This phase I/II trial investigated safety, pharmacokinetics and potential biomarkers of the histone deacetylase inhibitor resminostat and a combination therapy with resminostat and sorafenib.

Resminostat plus sorafenib as second-line therapy of advanced hepatocellular carcinoma - The SHELTER study

CILLO, UMBERTO;
2016

Abstract

No established therapies for patients with hepatocellular carcinoma (HCC) and progression on first-line sorafenib treatment currently exist. This phase I/II trial investigated safety, pharmacokinetics and potential biomarkers of the histone deacetylase inhibitor resminostat and a combination therapy with resminostat and sorafenib.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11577/3192641
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