Background: Elderly patients with breast cancer (BC) usually present a reduction of their quality of life (QoL) both before and after surgery compared to younger patients. The short-form (SF-36) of the Medical Outcomes Study (MOS) questionnaire has long been used in clinical practice for patient population survey and healthy policy evaluation. It is a 36-item questionnaire with eight scaled sections: a lower score corresponds to a more disease-related disability. The aim of this study was to evaluate the postoperative health-related QoL between elderly and younger patients after breast-conserving surgery in patients with early (N0) BC using the MOS-SF-36 questionnaire. Methods: Sixty-two consecutive patients (60.8±9.9 years) with confirmed pT1-2 N0 M0 BC requiring conservative surgery were prospectively enrolled in the study. There were 36 (58.1%) elderly (>65 years of age) and 26 (41.9%) nonelderly patients. Informed consent was obtained from each participant. The day before discharge after surgery, all patients were asked to report their functional limitations and health-related status by filling the following sections of the MOS-SF-36 (No. of items): bodily pain (2), emotional role functioning (3), general health perceptions (5), mental health (5), physical functioning (10), physical role functioning (4), social role functioning (2), vitality (4). The Mann-Whitney U-test was used to compare results. A p-value <0.05 was considered statistically significant. Results: The results are reported in the Table. In general, the health-related QoF after surgery was similar in both groups. However, the scores related to bodily pain (64.3±21.2 vs. 53.1±16.3, p=0.03), physical functioning (66.3±18.2 vs. 56.3±11.7, p=0.02) and vitality (56.7±13.6 vs. 50.1±8.7, p=0.03) reported by younger patients were higher than that reported by the elderly.
Short-term quality of life changes after surgery in elderly (>65 years) patients with breast cancer using the medical outcomes study short form (MOS-SF-36) questionnaire
LUMACHI, FRANCO;
2016
Abstract
Background: Elderly patients with breast cancer (BC) usually present a reduction of their quality of life (QoL) both before and after surgery compared to younger patients. The short-form (SF-36) of the Medical Outcomes Study (MOS) questionnaire has long been used in clinical practice for patient population survey and healthy policy evaluation. It is a 36-item questionnaire with eight scaled sections: a lower score corresponds to a more disease-related disability. The aim of this study was to evaluate the postoperative health-related QoL between elderly and younger patients after breast-conserving surgery in patients with early (N0) BC using the MOS-SF-36 questionnaire. Methods: Sixty-two consecutive patients (60.8±9.9 years) with confirmed pT1-2 N0 M0 BC requiring conservative surgery were prospectively enrolled in the study. There were 36 (58.1%) elderly (>65 years of age) and 26 (41.9%) nonelderly patients. Informed consent was obtained from each participant. The day before discharge after surgery, all patients were asked to report their functional limitations and health-related status by filling the following sections of the MOS-SF-36 (No. of items): bodily pain (2), emotional role functioning (3), general health perceptions (5), mental health (5), physical functioning (10), physical role functioning (4), social role functioning (2), vitality (4). The Mann-Whitney U-test was used to compare results. A p-value <0.05 was considered statistically significant. Results: The results are reported in the Table. In general, the health-related QoF after surgery was similar in both groups. However, the scores related to bodily pain (64.3±21.2 vs. 53.1±16.3, p=0.03), physical functioning (66.3±18.2 vs. 56.3±11.7, p=0.02) and vitality (56.7±13.6 vs. 50.1±8.7, p=0.03) reported by younger patients were higher than that reported by the elderly.Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
