Purpose – This paper aims to present the optimal design of an inductor used to heat a magnetic nanoparticle fluid injected in a cell culture inside a Petri dish. Design/methodology/approach – The inductor design is driven by means of a multi-objective optimization algorithm that generalizes the migration-non-dominated sorting genetic algorithm (NSGA); it is called self-adapting migration-NSGA. Findings – The optimized device is able to synthesize a uniform magnetic field in a nanoparticle fluid, substantially helping its heating capability. The ultimate scope is to assist the cancer therapy based on magnetic fluid hyperthermia (MFH). Originality/value – The optimal design of an inductor for MFH applications has been carried out by applying an improved version of migration-based NSGA-II algorithm including automatic stop and a self-adapting concept. The modified optimization algorithm is suitable to find better optimal solutions with respect to a standard version of NSGA-II.

Self-adaptive NGSA algorithm and optimal design of inductors for magneto-fluid hyperthermia

DUGHIERO, FABRIZIO;FORZAN, MICHELE;SIENI, ELISABETTA
2017

Abstract

Purpose – This paper aims to present the optimal design of an inductor used to heat a magnetic nanoparticle fluid injected in a cell culture inside a Petri dish. Design/methodology/approach – The inductor design is driven by means of a multi-objective optimization algorithm that generalizes the migration-non-dominated sorting genetic algorithm (NSGA); it is called self-adapting migration-NSGA. Findings – The optimized device is able to synthesize a uniform magnetic field in a nanoparticle fluid, substantially helping its heating capability. The ultimate scope is to assist the cancer therapy based on magnetic fluid hyperthermia (MFH). Originality/value – The optimal design of an inductor for MFH applications has been carried out by applying an improved version of migration-based NSGA-II algorithm including automatic stop and a self-adapting concept. The modified optimization algorithm is suitable to find better optimal solutions with respect to a standard version of NSGA-II.
2017
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11577/3223877
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 6
  • ???jsp.display-item.citation.isi??? 6
social impact