Biliary tract cancers (BTCs) are clinically and pathologically heterogeneous with poor response to treatments. Genomic profiling can offer a clearer understanding of their carcinogenesis, classification and treatment strategy. We performed large scale genome sequencing analyses on BTCs to investigate their somatic and germline driver events and characterize their genomic landscape.

Genomic Characterization of Biliary Tract Cancers Identifies Driver Genes and Predisposing Mutations

Fassan, Matteo;Scarpa, Aldo;
2018

Abstract

Biliary tract cancers (BTCs) are clinically and pathologically heterogeneous with poor response to treatments. Genomic profiling can offer a clearer understanding of their carcinogenesis, classification and treatment strategy. We performed large scale genome sequencing analyses on BTCs to investigate their somatic and germline driver events and characterize their genomic landscape.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11577/3256731
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