LiNbO3 integrated system for opto-microfluidic sensing

Bettella, G.; Zamboni, R.; Pozza, G.; Zaltron, A.; Montevecchi, C.; Pierno, M.; Mistura, G.; Sada, C.; Gauthier-Manuel, L.; Chauvet, M.

doi:10.1016/j.snb.2018.10.082

In this work, we realized and tested an integrated opto-microﬂuidics platform entirely made on lithium niobate (LiNbO3) crystals, able to detect the single droplet passage and estimate its size without the need of any imaging processing. It is based on the coupling of a self-aligned integrated optical stage, made of an array of optical waveguides, to a microﬂuidic circuit such as a T-junction or Cross-junction engraved in the same substrate. The platform presented high quality performances in terms of optical triggering, reproducibility and stability in time, allowing in real-time data analysis. The comparison with standard approaches using microscopes and fast camera imagining acquisition and relative post-processing, showed an increased capability better than 50%. The demonstrated feasibility of integration of these two stages will allow the realization of a Lab-On-a-Chip on a monolithic substrate of lithium niobate, exploiting its multiple applications for manipulation of droplets.

Titolo:	LiNbO3 integrated system for opto-microfluidic sensing
Autori:	Bettella, G. [Data Curation] ZAMBONI, RICCARDO [Investigation] Pozza, G. [Membro del Collaboration Group] ZALTRON, ANNAMARIA [Investigation] Montevecchi, C. PIERNO, MATTEO AMBROGIO PAOLO [Membro del Collaboration Group] MISTURA, GIAMPAOLO [Membro del Collaboration Group] SADA, CINZIA [Supervision] (Corresponding) Gauthier-Manuel, L. [Resources] Chauvet, M. [Writing – Review & Editing] mostra contributor esterni nascondi contributor esterni
Data di pubblicazione:	2019
Rivista:	SENSORS AND ACTUATORS. B, CHEMICAL
Abstract:	In this work, we realized and tested an integrated opto-microﬂuidics platform entirely made on lithium niobate (LiNbO3) crystals, able to detect the single droplet passage and estimate its size without the need of any imaging processing. It is based on the coupling of a self-aligned integrated optical stage, made of an array of optical waveguides, to a microﬂuidic circuit such as a T-junction or Cross-junction engraved in the same substrate. The platform presented high quality performances in terms of optical triggering, reproducibility and stability in time, allowing in real-time data analysis. The comparison with standard approaches using microscopes and fast camera imagining acquisition and relative post-processing, showed an increased capability better than 50%. The demonstrated feasibility of integration of these two stages will allow the realization of a Lab-On-a-Chip on a monolithic substrate of lithium niobate, exploiting its multiple applications for manipulation of droplets.
Handle:	http://hdl.handle.net/11577/3288641
Appare nelle tipologie:	01.01 - Articolo in rivista

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