Neurofibromatosis type 2 (NF2) is an autosomal dominant, multiple neoplasia syndrome characterized by bilateral vestibular schwannomas (VSs). Endoglin is a proliferation-associated protein expressed in angiogenic endothelial cells. The aim of this study was to investigate endoglin expression in a series of NF2-associated VSs, as compared with a group of sporadic VSs.
Endoglin (CD105) expression in neurofibromatosis type 2 vestibular schwannoma
Marioni, Gino
;Nicolè, Lorenzo;Cazzador, Diego;PAVONE, CHIARA;D'Avella, Domenico;Martini, Alessandro;Zanoletti, Elisabetta
2019
Abstract
Neurofibromatosis type 2 (NF2) is an autosomal dominant, multiple neoplasia syndrome characterized by bilateral vestibular schwannomas (VSs). Endoglin is a proliferation-associated protein expressed in angiogenic endothelial cells. The aim of this study was to investigate endoglin expression in a series of NF2-associated VSs, as compared with a group of sporadic VSs.
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