From fetal life until cardiac surgery, complex congenital heart diseases (CHD) exhibit different hemodynamic and oxygenation patterns that can lead to alteration of the metabolic profile. We used a metabolomic approach to identify urine metabolic markers before cardiac surgery, aiming to define the physiology of patients with complex CHD and to contribute to predict their neurodevelopmental outcome.
Pre-surgery urine metabolomics may predict late neurodevelopmental outcome in children with congenital heart disease
Vedovelli L.;Cogo P.;Cainelli E.;Suppiej A.;Padalino M.;Tassini M.;Simonato M.;Stellin G.;Buonocore G.;
2019
Abstract
From fetal life until cardiac surgery, complex congenital heart diseases (CHD) exhibit different hemodynamic and oxygenation patterns that can lead to alteration of the metabolic profile. We used a metabolomic approach to identify urine metabolic markers before cardiac surgery, aiming to define the physiology of patients with complex CHD and to contribute to predict their neurodevelopmental outcome.File in questo prodotto:
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