Hypocoagulability and impaired platelet function have been associated to a higher risk of death in sepsis. The aim of our cohort study was to determine whether sepsis-induced hypocoagulability (assessed by ROTEM®) and platelet dysfunction (assessed by MULTIPLATE®) were worse in septic patients who died within the first 28days compared with patients who died between days29-90.
Whole blood hypocoagulable profile correlates with the greater risk of death at 28 days in patients with severe sepsis
Boscolo, Annalisa;Spiezia, Luca;Campello, Elena;Bertini, Diana;Lucchetta, Vittorio;Piasentini, Eleonora;De Cassai, Alessandro;Simioni, Paolo
2020
Abstract
Hypocoagulability and impaired platelet function have been associated to a higher risk of death in sepsis. The aim of our cohort study was to determine whether sepsis-induced hypocoagulability (assessed by ROTEM®) and platelet dysfunction (assessed by MULTIPLATE®) were worse in septic patients who died within the first 28days compared with patients who died between days29-90.
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