Multiple endocrine neoplasia type 2A (MEN 2A) is a rare syndrome caused by RET germline mutations, and have been associated with primary hyperparathyroidism (PHPT) in up to 30% of cases. Recommendations on RET screening in patients with apparently sporadic PHPT are unclear. We aimed to estimate the prevalence of cases presenting with PHPT as first manifestation among MEN 2A index cases and to characterize the former cases.
Primary hyperparathyroidism as first manifestation in MEN 2A: an international multicenter study
Censi, Simona;Mian, Caterina;
2020
Abstract
Multiple endocrine neoplasia type 2A (MEN 2A) is a rare syndrome caused by RET germline mutations, and have been associated with primary hyperparathyroidism (PHPT) in up to 30% of cases. Recommendations on RET screening in patients with apparently sporadic PHPT are unclear. We aimed to estimate the prevalence of cases presenting with PHPT as first manifestation among MEN 2A index cases and to characterize the former cases.File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
Primary hyperparathyroidism as first manifestation in MEN 2A an international multicenter study.pdf
accesso aperto
Tipologia:
Postprint (accepted version)
Licenza:
Creative commons
Dimensione
310.78 kB
Formato
Adobe PDF
|
310.78 kB | Adobe PDF | Visualizza/Apri |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
