15 demented patients aged 56-71 years, who underwent a therapeutic trial with DL or L acetyl carnitine for a period ranging from 1 to 12 months were studied. A number of clinical and electrophysiological parameters (P 300) were evaluated before and after the trial to assess the effect of the drug. In about half of our patients an improvement in intellectual performance and behavior was observed, corresponding to a decrease of P 300 latencies. The mechanisms of action of acetyl carnitine in dementia are discussed.
Preliminary study on acetylcarnitine treatment of patients with mental deterioration
Angelini C.
Conceptualization
1982
Abstract
15 demented patients aged 56-71 years, who underwent a therapeutic trial with DL or L acetyl carnitine for a period ranging from 1 to 12 months were studied. A number of clinical and electrophysiological parameters (P 300) were evaluated before and after the trial to assess the effect of the drug. In about half of our patients an improvement in intellectual performance and behavior was observed, corresponding to a decrease of P 300 latencies. The mechanisms of action of acetyl carnitine in dementia are discussed.File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
