52gMn production route for multi-modal imaging applications

The radionuclide 52gMn is of significant medical interest for the innovative PET-MRI multimodal imaging technique. In this study we compare its standard cyclotron production route natCr(p, x)52gMn with the alternative reaction natV(α, x)52gMn. The theoretical calculations are performed by a suitable tuning of the nuclear level density parameters of the TALYS reaction code, with the aim to obtain a good agreement with the experimental cross sections. The production route with natV results in a more favorable radionuclidic purity than with natCr. Dosimetric studies are performed to establish the time frame in which 52gMn can be used with an acceptable dose to the patient.