Metabolic syndrome and andrological diseases

: Metabolic syndrome (MetS) and andrological diseases share common risk factors and common patho-physiological mechanism. In this comprehensive review we describe the relation between metabolic syndrome and male sexual disorders and we explore the available evidence of the molecular physiological mechanisms correlating these conditions. To describe the relation between metabolic syndrome and andrological diseases. Current literature shows strong evidence on the association between pathophysiological mechanisms at the base of metabolic syndrome and androurological diseases, such as premature ejaculation, erectile dysfunction and hypogonadism. Strong associations are seen between male sexual dysfunction and central obesity, poor glycemic control, hyperlipidemia, as well as hypertension. The constellation of risk factors that make up metabolic syndrome are linked to male sexual dysfunction and are largely modifiable. Therefore, effective interventions targeting the underlying pathophysiology have the potential to greatly impact and improve patient sexual function and, ultimately, quality of life.