Phosphorylated proteins are known to be present in multiple body fluids in normal conditions, and abnormally accumulated under some pathological conditions. The biological significance of their role in the extracellular space has started being elucidated only recently, for example in bone mineralization, neural development, and coagulation. Here, we address some criticalities of conventional culture systems for the study of the extracellular regulation of phosphorylation.

Extracellular phosphoprotein regulation is affected by culture system scale-down

Martewicz, Sebastian;Gagliano, Onelia;Elvassore, Nicola;Luni, Camilla
2022

Abstract

Phosphorylated proteins are known to be present in multiple body fluids in normal conditions, and abnormally accumulated under some pathological conditions. The biological significance of their role in the extracellular space has started being elucidated only recently, for example in bone mineralization, neural development, and coagulation. Here, we address some criticalities of conventional culture systems for the study of the extracellular regulation of phosphorylation.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11577/3452350
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