BackgroundAn enlarged right atrium (RA) is a challenging anatomy that can limit the successful use of His bundle pacing (HBP). It is unknown whether new implantation tools could help overcome these challenges. MethodsConsecutive patients with RA volume index >25 mL/m(2) in men and >21 mL/m(2) in women underwent permanent HBP. We used a stylet-driven lead (SDL) with an extendable helix delivered via a dedicated delivery sheath (Selectra 3D, Biotronik) as a first attempt. In case of failure, a second attempt was performed with the same lead but with a different delivery curve. Finally, a lumen-less lead (LLL) was also available as a third attempt. ResultsThe study cohort included 24 patients (median age 75.7 years [interquartile range, 70.9-79.0], 88% men) with a RA volume of 49 mL/m(2) (45-54). Using SDL, HBP was achieved with a single sheath curve in 17 patients (71%). The second attempt with the same lead but a different sheath was successful in four more patients (SDL success 87%). The fluoroscopy time increased significantly when the second attempt was necessary (8 min [6-11] vs. 15 min [13-17], p < .001). In the remaining three patients, HBP was further attempted with a LLL leading to a final procedural success of 96%. No lead dislodgment nor significant increase in pacing threshold was observed at 1-month (1.2 [0.7-1.7] V@1.0 ms vs. 1.1 [0.8-1.7] V@1.0 ms, p = .939). ConclusionThe availability of different dedicated delivery systems for HBP can improve procedural outcomes even in challenging circumstances, such as in patients with right atriomegaly.

Permanent His bundle pacing in patients with right atriomegaly: The value of different dedicated delivery sheaths

Giacopelli D.
2023

Abstract

BackgroundAn enlarged right atrium (RA) is a challenging anatomy that can limit the successful use of His bundle pacing (HBP). It is unknown whether new implantation tools could help overcome these challenges. MethodsConsecutive patients with RA volume index >25 mL/m(2) in men and >21 mL/m(2) in women underwent permanent HBP. We used a stylet-driven lead (SDL) with an extendable helix delivered via a dedicated delivery sheath (Selectra 3D, Biotronik) as a first attempt. In case of failure, a second attempt was performed with the same lead but with a different delivery curve. Finally, a lumen-less lead (LLL) was also available as a third attempt. ResultsThe study cohort included 24 patients (median age 75.7 years [interquartile range, 70.9-79.0], 88% men) with a RA volume of 49 mL/m(2) (45-54). Using SDL, HBP was achieved with a single sheath curve in 17 patients (71%). The second attempt with the same lead but a different sheath was successful in four more patients (SDL success 87%). The fluoroscopy time increased significantly when the second attempt was necessary (8 min [6-11] vs. 15 min [13-17], p < .001). In the remaining three patients, HBP was further attempted with a LLL leading to a final procedural success of 96%. No lead dislodgment nor significant increase in pacing threshold was observed at 1-month (1.2 [0.7-1.7] V@1.0 ms vs. 1.1 [0.8-1.7] V@1.0 ms, p = .939). ConclusionThe availability of different dedicated delivery systems for HBP can improve procedural outcomes even in challenging circumstances, such as in patients with right atriomegaly.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11577/3474572
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