Semple et al. review the literature to assess the effects of pharmacologic or surgical interventions in monogenic insulin resistance when stratified by genotype. The evidence guiding genotype-specific treatment of monogenic insulin resistance is of low to very low quality, but suggestive of benefits of metreleptin, thiazolidinediones, and rhIGF-1.

Genotype-stratified treatment for monogenic insulin resistance: a systematic review

Morieri M. L.;
2023

Abstract

Semple et al. review the literature to assess the effects of pharmacologic or surgical interventions in monogenic insulin resistance when stratified by genotype. The evidence guiding genotype-specific treatment of monogenic insulin resistance is of low to very low quality, but suggestive of benefits of metreleptin, thiazolidinediones, and rhIGF-1.
2023
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11577/3546143
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