STRPsearch Web Server: A User-friendly Interface for Rapid and Accurate Prediction of Structured Tandem Repeat Proteins

: Structured Tandem Repeat Proteins (STRPs) are a subset of repeat proteins characterized by recurring structural motifs, even in cases where sequence similarity between repeats is very low. Despite substantial sequence variability, STRPs preserve conserved secondary-structure elements that underpin a wide range of biological functions. Although millions of protein structures are now publicly available, the accurate detection of STRPs remains challenging. STRPsearch is a recently developed tool for the rapid identification and classification of STRPs. Here, we introduce the STRPsearch web server, an enhanced implementation featuring a user-friendly interface. The server is freely available https://strpsearch.biocomputingup.it/.