Sfoglia per Autore
Dysfunction in endocannabinoids, palmitoylethanolamide, and degradation of tryptophan into kynurenine in individuals with depressive symptoms
2024 Comai, Stefano; Nunez, Nicolas; Atkin, Tobias; Ghabrash, Maykel F; Zakarian, Rita; Fielding, Allan; Saint-Laurent, Marie; Low, Nancy; Sauber, Garrett; Ragazzi, Eugenio; Hillard, Cecilia J; Gobbi, Gabriella
The kynurenine pathway in treatment-resistant schizophrenia at the crossroads between pathophysiology and pharmacotherapy
2024 Sapienza, Jacopo; Agostoni, Giulia; Dall'Acqua, Stefano; Sut, Stefania; Nasini, Sofia; Martini, Francesca; Marchesi, Anna; Bechi, Margherita; Buonocore, Mariachiara; Cocchi, Federica; Cavallaro, Roberto; Spangaro, Marco; Comai, Stefano; Bosia, Marta
Probing the Association between Cognition, Suicidal Behavior and Tryptophan Metabolism in a Sample of Individuals Living with Bipolar Disorder: A Secondary Analysis
2023 Paribello, Pasquale; Squassina, Alessio; Pisanu, Claudia; Meloni, Anna; Dall'Acqua, Stefano; Sut, Stefania; Nasini, Sofia; Bertazzo, Antonella; Congiu, Donatella; Garzilli, Mario; Guiso, Beatrice; Suprani, Federico; Pulcinelli, Vittoria; Iaselli, Maria Novella; Pinna, Ilaria; Somaini, Giulia; Arru, Laura; Corrias, Carolina; Pinna, Federica; Carpiniello, Bernardo; Comai, Stefano; Manchia, Mirko
Age-Related Effects of Exogenous Melatonin on Anxiety-like Behavior in C57/B6J Mice
2023 Nasini, Sofia; Tidei, Sara; Shkodra, Atea; De Gregorio, Danilo; Cambiaghi, Marco; Comai, Stefano
Biological Factors Underpinning Suicidal Behaviour: An Update
2023 Abou Chahla, Maya N; Khalil, Mahmoud I; Comai, Stefano; Brundin, Lena; Erhardt, Sophie; Guillemin, Gilles J
The novel uncompetitive NMDA receptor antagonist esmethadone (REL-1017) has no meaningful abuse potential in recreational drug users
2023 Shram, Megan J; Henningfield, Jack E; Apseloff, Glen; Gorodetzky, Charles W; De Martin, Sara; Vocci, Frank L; Sapienza, Frank L; Kosten, Thomas R; Huston, Jeff; Buchhalter, August; Ashworth, Judy; Lanier, Ryan; Folli, Franco; Mattarei, Andrea; Guidetti, Clotilde; Comai, Stefano; O'Gorman, Cedric; Traversa, Sergio; Inturrisi, Charles E; Manfredi, Paolo L; Pappagallo, Marco
Substantially elevated serum glutamate and CSF GOT-1 levels associated with cerebral ischemia and poor neurological outcomes in subarachnoid hemorrhage patients
2023 Snider, Silvia; Albano, Luigi; Gagliardi, Filippo; Comai, Stefano; Roncelli, Francesca; De Domenico, Pierfrancesco; Pompeo, Edoardo; Panni, Pietro; Bens, Nicole; Calvi, Maria Rosa; Mortini, Pietro; Ruban, Angela
Importance of the dysregulation of the kynurenine pathway on cognition in schizophrenia: a systematic review of clinical studies
2023 Sapienza, Jacopo; Spangaro, Marco; Guillemin, Gilles J; Comai, Stefano; Bosia, Marta
Sleep Quality After Quetiapine Augmentation in Patients With Treatment-Resistant Depression and Personality Disorders
2023 Moderie, Christophe; King, Jacob D; Nuñez, Nicolas; Comai, Stefano; Gobbi, Gabriella
Activation of Kv7 channels normalizes hyperactivity of the VTA-NAcLat circuit and attenuates methamphetamine-induced conditioned place preference and sensitization in mice
2023 Liu, E; Pang, Kunkun; Liu, Min; Tan, Xu; Hang, Zhaofang; Mu, Shouhong; Han, Weikai; Yue, Qingwei; Comai, Stefano; Sun, Jinhao
Esmethadone-HCl (REL-1017): a promising rapid antidepressant
2023 Fava, Maurizio; Stahl, Stephen M; De Martin, Sara; Mattarei, Andrea; Bettini, Ezio; Comai, Stefano; Alimonti, Andrea; Bifari, Francesco; Pani, Luca; Folli, Franco; Guidetti, Clotilde; Furlan, Alberto; Sgrignani, Jacopo; Locatelli, Patrizia; Cavalli, Andrea; O'Gorman, Cedric; Traversa, Sergio; Inturrisi, Charles E; Pappagallo, Marco; Manfredi, Paolo L
Effects of repeated lysergic acid diethylamide (LSD) on the mouse brain endocannabinoidome and gut microbiome
2023 Inserra, Antonio; Giorgini, Giada; Lacroix, Sebastien; Bertazzo, Antonella; Choo, Jocelyn; Markopolous, Athanasios; Grant, Emily; Abolghasemi, Armita; De Gregorio, Danilo; Flamand, Nicolas; Rogers, Geraint; Comai, Stefano; Silvestri, Cristoforo; Gobbi, Gabriella; Di Marzo, Vincenzo
Melatonin MT1 receptors as a target for the psychopharmacology of bipolar disorder: A translational study
2023 Tassan Mazzocco, Margherita; Pisanu, Claudia; Russo, Luigi; Acconcia, Clementina; Cambiaghi, Marco; De Girolamo, Sofia; Squassina, Alessio; Cherchi, Laura; Monzani, Elena; Scebba, Francesca; Angeloni, Debora; De Gregorio, Danilo; Nasini, Sofia; Dall'Acqua, Stefano; Sut, Stefania; Suprani, Federico; Garzilli, Mario; Guiso, Beatrice; Pulcinelli, Vittoria; Iaselli, Maria Novella; Pinna, Ilaria; Somaini, Giulia; Arru, Laura; Corrias, Carolina; Paribello, Pasquale; Pinna, Federica; Gobbi, Gabriella; Valtorta, Flavia; Carpiniello, Bernardo; Manchia, Mirko; Comai, Stefano
Selective association of cytokine levels and kynurenine/tryptophan ratio with alterations in white matter microstructure in bipolar but not in unipolar depression
2022 Comai, S.; Melloni, E.; Lorenzi, C.; Bollettini, I.; Vai, B.; Zanardi, R.; Colombo, C.; Valtorta, F.; Benedetti, F.; Poletti, S.
Distinct Effects of Antidepressants in Association with Mood Stabilizers and/or Antipsychotics in Unipolar and Bipolar Depression
2022 Moderie, C.; Nunez, N.; Comai, S.; Saint-Laurent, M.; Fielding, A.; Low, N.; Gobbi, G.
Sex Differences in Responses to Antidepressant Augmentations in Treatment-Resistant Depression
2022 Moderie, Christophe; Nuñez, Nicolas; Fielding, Allan; Comai, Stefano; Gobbi, Gabriella
Is Poor Lithium Response in Individuals with Bipolar Disorder Associated with Increased Degradation of Tryptophan along the Kynurenine Pathway? Results of an Exploratory Study
2022 Fellendorf, Frederike T; Manchia, Mirko; Squassina, Alessio; Pisanu, Claudia; Dall'Acqua, Stefano; Sut, Stefania; Nasini, Sofia; Congiu, Donatella; Reininghaus, Eva Z; Garzilli, Mario; Guiso, Beatrice; Suprani, Federico; Paribello, Pasquale; Pulcinelli, Vittoria; Iaselli, Maria Novella; Pinna, Ilaria; Somaini, Giulia; Arru, Laura; Corrias, Carolina; Pinna, Federica; Carpiniello, Bernardo; Comai, Stefano
Acute and Chronic Pain Preclinical Models to Study the Analgesic Properties of Melatonergic Compounds
2022 De Gregorio, Danilo; Comai, Stefano
Investigation of Genetic Variants Associated with Tryptophan Metabolite Levels via Serotonin and Kynurenine Pathways in Patients with Bipolar Disorder
2022 Pisanu, Claudia; Squassina, Alessio; Paribello, Pasquale; Dall'Acqua, Stefano; Sut, Stefania; Nasini, Sofia; Bertazzo, Antonella; Congiu, Donatella; Meloni, Anna; Garzilli, Mario; Guiso, Beatrice; Suprani, Federico; Pulcinelli, Vittoria; Iaselli, Maria Novella; Pinna, Ilaria; Somaini, Giulia; Arru, Laura; Corrias, Carolina; Pinna, Federica; Carpiniello, Bernardo; Comai, Stefano; Manchia, Mirko
Melatonin and aggressive behavior: A systematic review of the literature on preclinical and clinical evidence
2022 Paribello, P.; Manchia, M.; Bosia, M.; Pinna, F.; Carpiniello, B.; Comai, S.
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