SOSIC, ALICE
SOSIC, ALICE
Dipartimento di Scienze del Farmaco - DSF
Insights into the complexity of SARS-CoV-2 Mpro inhibition: Ebselen and its derivatives impair dimerisation of the enzyme
2026 Fabbian, S.; Fabi, S.; Schwarz, L.; Preto, G.; Schiavinato, C.; Salata, C.; Crocetti, L.; Battistutta, R.; Gatto, B.; Sosic, A.
Catechol-induced covalent modifications modulate the aggregation tendency of α-synuclein: An in-solution and in-silico study
2025 Inciardi, Ilenia; Rizzotto, Elena; Gregoris, Francesco; Fongaro, Benedetta; Sosic, Alice; Minervini, Giovanni; Polverino De Laureto, Patrizia
Native-MS as a suitable tool to select new scaffold for the inhibition of protein aggregation
2025 Fongaro, Benedetta; Trolese, Philipp; Scapin, Vittoria; Sosic, Alice; Acquasaliente, Laura; Polverino De Laureto, Patrizia
Recent breakthroughs in synthetic small molecules targeting SARS-CoV-2 Mpro from 2022 to 2024
2025 Braconi, Laura; Sosic, Alice; Crocetti, Letizia
The aggregation kinetics of α-Synuclein is highly dependent on the protein dynamics in the native state
2025 Fongaro, Benedetta; Trolese, Philipp; Scapin, Vittoria; Sosic, Alice; Acquasaliente, Laura; Polverino De Laureto, Patrizia
The native-state dynamics of α-Synuclein plays a crucial role in determining its aggregation kinetics
2025 Fongaro, Benedetta; Trolese, Philipp; Scapin, V.; Sosic, Alice; Acquasaliente, Laura; Polverino De Laureto, Patrizia
The OSCP Subunit of ATP Synthase is a Dimer in Solution: Strategy to Induce the Monomeric Protein as a New Tool for Drug Discovery
2025 Fabbian, Simone; Gabbatore, Laura; Morbiato, Laura; Zotti, Marta De; Giorgio, Valentina; Battistutta, Roberto; Giachin, Gabriele; Sosic, Alice; Bellanda, Massimo
Allostery in homodimeric SARS-CoV-2 main protease
2024 Fornasier, Emanuele; Fabbian, Simone; Shehi, Haidi; Enderle, Janine; Gatto, Barbara; Volpin, Daniele; Biondi, Barbara; Bellanda, Massimo; Giachin, Gabriele; Sosic, Alice; Battistutta, Roberto
In Vitro Chemical Mapping of G-Quadruplex DNA Structures by Bis-3-Chloropiperidines
2023 Sosic, Alice; Dal Lago, Cristina; Goettlich, Richard; Gatto, Barbara
3,4-Dihydroxyphenylethanol and 3,4-dihydroxyphenylacetic acid affect the aggregation process of E46K variant of α-synuclein at different extent: Insights into the interplay between protein dynamics and catechol effect
2022 Fongaro, Benedetta; Cappelletto, Elia; Sosic, Alice; Spolaore, Barbara; Polverino De Laureto, Patrizia
A new inactive conformation of SARS-CoV-2 main protease
2022 Fornasier, Emanuele; Macchia, Maria Ludovica; Giachin, Gabriele; Sosic, Alice; Pavan, Matteo; Sturlese, Mattia; Salata, Cristiano; Moro, Stefano; Gatto, Barbara; Bellanda, Massimo; Battistutta, Roberto
Computationally driven discovery of SARS-CoV-2 Mpro inhibitors: from design to experimental validation
2022 El Khoury, Léa; Jing, Zhifeng; Cuzzolin, Alberto; Deplano, Alessandro; Loco, Daniele; Sattarov, Boris; Hédin, Florent; Wendeborn, Sebastian; Ho, Chris; El Ahdab, Dina; Jaffrelot-Inizan, Theo; Sturlese, M; Sosic, Alice; Volpiana, Martina; Lugato, Angela; Barone, Marco; Gatto, Barbara; Macchia, Maria Ludovica.; Bellanda, M; Battistutta, Roberto; Salata, Cristiano; Kondratov, Ivan; Iminov, Rustan; Khairulin, Andrii; Mykhalonok, Yaroslav; Pochepko, Anton; Chashka-Ratushnyi, Volodymyr; Kos, Iaroslava; Moro, Stefano; Montes, Matthieu; Ren, Pengyu; Ponder, Jay W.; Lagardère, Louis; Piquemal, Jean-Philip; Sabbadin, Davide
In Vitro Evaluation of Bis-3-Chloropiperidines as RNA Modulators Targeting TAR and TAR-Protein Interaction
2022 Sosic, A.; Olivato, G.; Carraro, C.; Gottlich, R.; Fabris, D.; Gatto, B.
Multifaceted Aspects of HIV-1 Nucleocapsid Inhibition by TAR-Targeting Peptidyl-Anthraquinones Bearing Terminal Aromatic Moieties
2022 Sosic, Alice; Frecentese, Francesco; Olivato, Giulia; Rollo, Daniele; Carraro, Caterina; Gamba, Elia; Santagada, Vincenzo; Gatto, Barbara
Appended Aromatic Moieties in Flexible Bis‐3‐chloropiperidines Confer Tropism against Pancreatic Cancer Cells
2021 Carraro, Caterina; Helbing, Tim; Francke, Alexander; Zuravka, Ivonne; Sosic, Alice; De Franco, Michele; Gandin, Valentina; Gatto, Barbara; Göttlich, D. Richard
B-CePs as cross-linking probes for the investigation of RNA higher-order structure
2021 Sosic, Alice; Göttlich, Richard; Fabris, Dan; Gatto, Barbara
Bis-3-Chloropiperidines Targeting TAR RNA as A Novel Strategy to Impair the HIV-1 Nucleocapsid Protein
2021 Sosic, Alice; Olivato, Giulia; Carraro, Caterina; Göttlich, Richard; Fabris, Dan; Gatto, Barbara
DNA-Binding Properties of Cytotoxic Naphtindolizinedione-Carboxamides Acting as Type II Topoisomerase Inhibitors. A Combined In Silico and Experimental Study
2021 Defant, Andrea; Gatti, Paolo; Poli, Alessandro; Serena, Marta; Sosic, Alice; Gatto, Barbara; Mancini, Ines
Aromatic Linkers Unleash the Antiproliferative Potential of 3-Chloropiperidines Against Pancreatic Cancer Cells
2020 Helbing, Tim; Carraro, Caterina; Francke, Alexander; Sosic, Alice; De Franco, Michele; Gandin, Valentina; Göttlich, Richard; Gatto, Barbara
Multiple in Vitro Inhibition of HIV-1 Proteins by 2,6-Dipeptidyl-anthraquinone Conjugates Targeting the PBS RNA
2020 Gamba, Elia; Sosic, Alice; Saccone, Irene; Magli, Elisa; Frecentese, Francesco; Gatto, Barbara