RUNFOLA, Massimiliano
RUNFOLA, Massimiliano
Dipartimento di Scienze del Farmaco - DSF
Design, synthesis and biological evaluation of new H2S-releasing rivastigmine derivatives as neuroprotective molecules
2025 Sestito, S; Cirone, I; Sagona, S; Runfola, M; Raffellini, L; La Rocca, V; Citi, V; Martelli, A; Daniele, S; Lai, M; Calderone, V; Martini, C; Manera, C; Rapposelli, S
Novel Thyroid Hormone Receptor-β Agonist TG68 Exerts Anti-Inflammatory, Lipid-Lowering and Anxiolytic Effects in a High-Fat Diet (HFD) Mouse Model of Obesity
2025 Polini, Beatrice; Ricardi, Caterina; Di Lupo, Francesca; Runfola, Massimiliano; Bacci, Andrea; Rapposelli, Simona; Bizzarri, Ranieri; Scalese, Marco; Saponaro, Federica; Chiellini, Grazia
Novel thyroid hormone receptor-β (TRβ) agonist as a promising multitarget agent for the treatment of interlinked diseases such as obesity and neurodegenerative disorders (NDD)
2024 Polini, B; Ricardi, C; Dettori, C; Carnicelli, V; Runfola, M; Rapposeli, S; Chiellini, G; Saponaro, F
Novel thyroid hormone receptor-β (TRβ) agonist as a promising multitarget agent for the treatment of interlinked diseases such as obesity and neurodegenerative disorders (NDD)
2024 Polini, B; Ricardi, C; Dettori, C; Carnicelli, V; Runfola, M; Rapposeli, S; Chiellini, G; Saponaro, F
Synthetic Thyroid Hormone Receptor-β Agonists Promote Oligodendrocyte Precursor Cell Differentiation in the Presence of Inflammatory Challenges
2023 Baldassarro, V. A.; Quadalti, C.; Runfola, M.; Manera, C.; Rapposelli, S.; Calza, L.
Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids
2022 Bacci, Andrea; Corsi, Francesca; Runfola, Massimiliano; Sestito, Simona; Piano, Ilaria; Manera, Clementina; Saccomanni, Giuseppe; Gargini, Claudia; Rapposelli, Simona
Development of potent dual PDK1/AurA kinase inhibitors for cancer therapy: Lead-optimization, structural insights, and ADME-Tox profile
2021 Sestito, S.; Bacci, A.; Chiarugi, S.; Runfola, M.; Gado, F.; Margheritis, E.; Gul, S.; Riveiro, M. E.; Vazquez, R.; Huguet, S.; Manera, C.; Rezai, K.; Garau, G.; Rapposelli, S.
Diphenyl-methane based thyromimetic inhibitors for transthyretin amyloidosis
2021 Kim, B.; Ko, Y. H.; Runfola, M.; Rapposelli, S.; Ortore, G.; Chiellini, G.; Kim, J. H.
Identification of a Thyroid Hormone Derivative as a Pleiotropic Agent for the Treatment of Alzheimer's Disease
2021 Runfola, Massimiliano; Perni, Michele; Yang, Xiaoting; Marchese, Maria; Bacci, Andrea; Mero, Serena; Santorelli, Filippo M; Polini, Beatrice; Chiellini, Grazia; Giuliani, Daniela; Vilella, Antonietta; Bodria, Martina; Daini, Eleonora; Vandini, Eleonora; Rudge, Simon; Gul, Sheraz; Wakelam, Michale O J; Vendruscolo, Michele; Rapposelli, Simona
Late breaker posters
2021 Perra, Andrea; Anna Kowalik, Marta; Serra, Marina; Runfola, Massimiliano; Rapposelli, Simona; Columbano., Amedeo
Novel liver-specific thyromimetics for the treatment of steatohepatitis
2021 Perra, A; Kowalik, Ma; Serra, M; Runfola, M; Rapposelli, S; Columbano, A
Novel liver-specific thyromimetics for the treatment of steatohepatitis
2021 Perra, A; Kowalik, Ma; Serra, M; Runfola, M; Rapposelli, S; Columbano, A
Potential role of two novel agonists of thyroid hormone receptor-β on liver regeneration (vol 53, e12808, 2020)
2021 Perra, A; Kowalik, Ma; Cabras, L; Runfola, M; Sestito, S; Migliore, C; Giordano, S; Chiellini, G; Rapposelli, S; Columbano, A
SG‐2: A SYNTHETIC ANALOG OF THYROID HORMONE METABOLITE 3‐IODOTHYRONAMINE (T1AM), PREVENTS β‐AMYLOID NEUROTOXICITY IN VITRO
2021 Polini, Beatrice; Carnicelli, Vittoria; Runfola, Massimiliano; Rapposelli, Simona; Zucchi, Riccardo; Chiellini, Grazia
TG68, a Novel Thyroid Hormone Receptor-β Agonist for the Treatment of NAFLD
2021 Caddeo, Andrea; Kowalik, Marta Anna; Serra, Marina; Runfola, Massimiliano; Bacci, Andrea; Rapposelli, Simona; Columbano, Amedeo; Perra, Andrea
Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics
2020 Runfola, M.; Sestito, S.; Gul, S.; Chiellini, G.; Rapposelli, S.
Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics
2020 Runfola, M; Sestito, S; Gul, S; Chiellini, G; Rapposelli, S
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis
2020 Runfola, Massimiliano; Sestito, Simona; Bellusci, Lorenza; La Pietra, Valeria; D'Amore, Vincenzo Maria; Kowalik, Marta Anna; Chiellini, Grazia; Gul, Sheraz; Perra, Andrea; Columbano, Amedeo; Marinelli, Luciana; Novellino, Ettore; Rapposelli, Simona
Potential role of two novel agonists of thyroid hormone receptor-β on liver regeneration
2020 Perra, A.; Kowalik, M. A.; Cabras, L.; Runfola, M.; Sestito, S.; Migliore, C.; Giordano, S.; Chiellini, G.; Rapposelli, S.; Columbano, A.
Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease?
2019 Sestito, S.; Pruccoli, L.; Runfola, M.; Citi, V.; Martelli, A.; Saccomanni, G.; Calderone, V.; Tarozzi, A.; Rapposelli, S.