Desantis, Jenny
Desantis, Jenny
Dipartimento di Medicina Molecolare - DMM
Discovery of a tetrahydrobenzothiophen-2-yl-pyrazolo[1,5-a]pyrimidine-3-carboxamide-based PROTAC as degrader of SARS-CoV-2 main protease
2026 Eleuteri, Michela; Bazzacco, Alessandro; Mercorelli, Beatrice; Desantis, Jenny; Zago, Alessia; Cruciani, Gabriele; Loregian, Arianna; Goracci, Laura
Novel SARS-CoV-2 allosteric inhibitors that destabilize the Main Protease Mpro dimer
2025 Mercorelli, B.; Bazzacco, A.; Eleuteri, M.; Di Cristofano, S.; Desantis, J.; Paciaroni, A.; Ortore, M. G.; Tuci, S.; Spinozzi, F.; Raimondo, D.; Goracci, L.; Cruciani, G.; Loregian, A.
Design, synthesis, and biological evaluation of first-in-class indomethacin-based PROTACs degrading SARS-CoV-2 main protease and with broad-spectrum antiviral activity
2024 Desantis, Jenny; Bazzacco, Alessandro; Eleuteri, Michela; Tuci, Sara; Bianconi, Elisa; Macchiarulo, Antonio; Mercorelli, Beatrice; Loregian, Arianna; Goracci, Laura
Discovery of novel SARS-CoV-2 inhibitors targeting the main protease Mpro by virtual screenings and hit optimization
2022 Mercorelli, Beatrice; Desantis, Jenny; Celegato, Marta; Bazzacco, Alessandro; Siragusa, Lydia; Benedetti, Paolo; Eleuteri, Michela; Croci, Federico; Cruciani, Gabriele; Goracci, Laura; Loregian, Arianna
Indomethacin-based PROTACs as pan-coronavirus antiviral agents
2021 Desantis, J.; Mercorelli, B.; Celegato, M.; Croci, F.; Bazzacco, A.; Baroni, M.; Siragusa, L.; Cruciani, G.; Loregian, A.; Goracci, L.