CALO', GIROLAMO
 Distribuzione geografica
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Continente #
NA - Nord America 7.750
EU - Europa 592
AS - Asia 381
SA - Sud America 6
AF - Africa 2
OC - Oceania 1
Totale 8.732
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Nazione #
US - Stati Uniti d'America 7.740
VN - Vietnam 278
FI - Finlandia 153
IT - Italia 138
GB - Regno Unito 108
CN - Cina 85
SE - Svezia 57
DE - Germania 56
IE - Irlanda 28
UA - Ucraina 15
NL - Olanda 10
CA - Canada 8
FR - Francia 5
RU - Federazione Russa 5
BE - Belgio 4
BG - Bulgaria 4
CL - Cile 4
JP - Giappone 4
EG - Egitto 2
HK - Hong Kong 2
HU - Ungheria 2
IR - Iran 2
JM - Giamaica 2
KR - Corea 2
AM - Armenia 1
AR - Argentina 1
AT - Austria 1
BR - Brasile 1
CH - Svizzera 1
EE - Estonia 1
GR - Grecia 1
LK - Sri Lanka 1
LU - Lussemburgo 1
MY - Malesia 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PH - Filippine 1
PL - Polonia 1
SA - Arabia Saudita 1
SG - Singapore 1
TH - Thailandia 1
UZ - Uzbekistan 1
Totale 8.732
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Città #
Fairfield 2.186
Woodbridge 651
Cambridge 631
Houston 603
Ashburn 522
San Diego 498
Seattle 463
Medford 389
Princeton 389
Des Moines 289
Wilmington 287
Dong Ket 278
Ann Arbor 197
Helsinki 150
Chandler 140
Roxbury 116
Padova 43
Beijing 34
London 34
Dublin 28
Norwalk 22
Ferrara 21
Kharkiv 15
Borås 11
New York 9
Prescot 9
Modena 8
Acton 7
Kilburn 7
Rockville 7
Chiswick 6
Ferrara di Monte Baldo 6
Hounslow 6
Milan 6
New Bedfont 6
Rome 5
Sofia 4
Brussels 3
Chicago 3
Cordovado 3
Misterbianco 3
Osaka 3
Piazzola sul Brenta 3
Southwark 3
Wandsworth 3
Austin 2
Bucheon-si 2
Budapest 2
Catania 2
Hong Kong 2
Lappeenranta 2
Las Vegas 2
Legnaro 2
Marano sul Panaro 2
Montego Bay 2
Niederzier 2
Paris 2
Raleigh 2
Redwood City 2
Riva 2
Tanta 2
Agordo 1
Andover 1
Andria 1
Antwerpen 1
Atlanta 1
Auckland 1
Bari 1
Belluno 1
Boardman 1
Bologna 1
Brooklyn 1
Busto Arsizio 1
Campagna Lupia 1
Colombo 1
Deventer 1
Dover 1
Dronten 1
Frankfurt am Main 1
Geislingen an der Steige 1
Grassano 1
Greenwich 1
Hanover 1
Innsbruck 1
Irving 1
Islington 1
Kashan 1
Kuala Lumpur 1
Kyoto 1
La Canada Flintridge 1
Landshut 1
Lincoln 1
Los Angeles 1
Luxembourg 1
Manila 1
Marineo 1
Miami 1
Monmouth Junction 1
Naaldwijk 1
Nanjing 1
Totale 8.178
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Nome #
1,4-Dioxolane-triazaspirodecanone derivatives as nociceptin/orphanin FQ receptor ligands 148
Hyaluronic Acid Induces Activation of the κ-Opioid Receptor 116
A simple method for electrical field stimulation of cultured granule cells 54
Acute and chronic antiparkinsonian effects of the novel nociceptin/orphanin FQ receptor antagonist NiK-21273 in comparison with SB-612111 52
Excitatory amino acids (EAAs) stimulate phosphatidylinositol turnover in adult rat striatal slices: interaction between NMDA and EAA metabotropic receptors 50
Novel Mixed NOP/Opioid Receptor Peptide Agonists 45
A novel and facile synthesis of tetra branched derivatives of nociceptin/orphanin FQ 43
[D-Pen(p-tBuBzl)5]NPS, a novel ligand for the neuropeptide S receptor: structure activity and pharmacological studies 41
In vitro functional characterization of novel nociceptin/orphanin FQ receptor agonists in recombinant and native preparations 40
In vitro and in vivo pharmacological characterization of a neuropeptide S tetrabranched derivative 40
In vitro and in vivo pharmacological characterization of nociceptin/orphanin FQ tetrabranched derivatives 40
Stress induces reinstatement of extinguished cocaine conditioned place preference by a sequential signaling via neuropeptide S, orexin, and endocannabinoid 39
Pharmacological characterization of tachykinin tetrabranched derivatives 39
Functional Selectivity Does Not Predict Antinociceptive/Locomotor Impairing Potencies of NOP Receptor Agonists 38
Activation of the nociceptin/orphanin FQ receptor reduces bronchoconstriction and microvascular leakage in a rabbit model of gastroesophageal reflux 38
Noradrenergic modulation of gamma-aminobutyric acid outflow from the human cerebral cortex 37
Beta-arrestin 2 rather than G protein efficacy determines the anxiolytic- versus antidepressant-like effects of nociceptin/orphanin FQ receptor ligands 37
(2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist 37
In vitro pharmacological characterization of a novel unbiased NOP receptor-selective nonpeptide agonist AT-403 37
Hypothalamic neuropeptide S receptor blockade decreases discriminative cue-induced reinstatement of cocaine seeking in the rat 36
Nociceptin Modulates Bronchoconstriction Induced by Sensory Nerve Activation in Mouse Lung 36
Actual concept of "probiotics": is it more functional to science or business? 36
In vitro and in vivo pharmacological characterization of Pronetupitant, a prodrug of the neurokinin 1 receptor antagonist Netupitant 36
Characterization of Halyomorpha halys TAR1 reveals its involvement in (E)-2-decenal pheromone perception 36
Structure-Activity Relationship Studies on Oxazolo[3,4-a]pyrazine Derivatives Leading to the Discovery of a Novel Neuropeptide S Receptor Antagonist with Potent In Vivo Activity 36
[(t)Bu-d-Gly(5)]NPS, a pure and potent antagonist of the neuropeptide S receptor: In vitro and in vivo studies 35
Circadian variation in attempted suicide by deliberate self-poisoning 35
Partial agonist behaviour depends upon the level of nociceptin/orphanin FQ receptor expression - studies using the ecdysone inducible mammalian expression system 35
Blockade of adenosine A2A receptor counteracts neuropeptide-S-induced hyperlocomotion in mice 35
Synthesis of mixed MOR/KOR efficacy cyclic opioid peptide analogs with antinociceptive activity after systemic administration 35
Activation of nociceptin/orphanin FQ receptors inhibits contextual fear memory reconsolidation 35
Pharmacological Assays for Investigating the NOP Receptor 34
A new ligand for the urotensin II receptor 34
Detailed in vitro pharmacological characterization of the clinically viable nociceptin/orphanin FQ peptide receptor antagonist BTRX-246040 34
Desensitisation of native and recombinant human urotensin-II receptors 34
Cyclic mu-opioid receptor ligands containing multiple N-methylated amino acid residues 34
Effects of non-peptide nociceptin/orphanin FQ receptor ligands on methylphenidate-induced hyperactivity in mice: Implications for bipolar disorders 34
A staged screening of registered drugs highlights remyelinating drug candidates for clinical trials 34
Pharmacology of the Kallikrein-Kinin system 34
Pharmacological characterization of naloxegol: In vitro and in vivo studies 34
Ligands Raise the Constraint That Limits Constitutive Activation in G Protein-coupled Opioid Receptors 33
Effect of neuropeptide S receptor antagonists and partial agonists on palatable food consumption in the rat 33
Acute thrombosis of abdominal aorta in a petient under warfarin treatment 33
Further studies at neuropeptide s position 5: discovery of novel neuropeptide S receptor antagonists 33
The Nociceptin/Orphanin FQ Receptor Antagonist UFP-101 Reduces Microvascular Inflammation to Lipopolysaccharide In Vivo. 33
Spinal antinociceptive effects of the novel NOP receptor agonist PWT2-nociceptin/orphanin FQ in mice and monkeys 32
Further studies on the pharmacological profile of the neuropeptide S receptor antagonist SHA 68 32
Nociceptin/orphanin FQ receptor knockout rats: in vitro and in vivo studies 32
Pharmacological profile of nociceptin/orphanin FQ receptors interacting with G-proteins and β-arrestins 2 32
Modulation of Drosophila suzukii type 1 tyramine receptor (DsTAR1) by monoterpenes: a potential new target for next generation biopesticides 32
[(pF)Phe(4), Arg(14), Lys(15)]N/OFQ-NH2 (UFP-102), a highly potent and selective agonist of the nociceptin/orphanin FQ receptor 32
Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonist 32
Modulation of Silent and Constitutively Active Nociceptin/Orphanin FQ Receptors by Potent Receptor Antagonists and Na+ Ions in Rat Sympathetic Neurons 32
1999, Pharmacological characterisation of the first non-peptide bradykinin B2 receptor agonist FR 190997: an in vitro study on human, rabbit and pig vascular B2 receptors 32
Characterisation of the novel mixed Mu-NOP peptide ligand dermorphin-N/OFQ (DeNo) 32
Neuropeptide S counteracts 6-OHDA-induced motor deficits in mice 32
Sudden death from pulmonary thromboembolism: chronobiological aspects 32
The concise guide to pharmacology 2019/20: G protein-coupled receptors 32
Structure-activity studies of the Phe(4) residue of nociceptin(1-13)-NH2: Identification of highly potent agonists of the nociceptin/orphanin FQ receptor 32
Neuropeptide S stimulates human monocyte chemotaxis via NPS receptor activation 32
Neuropeptide S produces hyperlocomotion and prevents oxidative stress damage in the mouse brain: A comparative study with amphetamine and diazepam 32
Urotensin II evokes neurotransmitter release from rat cerebrocortical slices 32
EMERGENCY ADMISSIONS OF OPIOID DRUG-ABUSERS FOR OVERDOSE - A CHRONOBIOLOGICAL STUDY OF ENHANCED RISK 32
[Dmt(1) ]N/OFQ(1-13)-NH(2) , a potent nociceptin/orphanin FQ and opioid receptor universal agonist 32
Intrathecal administration of nociceptin/orphanin FQ receptor agonists in rats: A strategy to relieve chemotherapy-induced neuropathic hypersensitivity 32
Anxiolytic- and panicolytic-like effects of Neuropeptide S in the mouse elevated T-maze 32
Circadian variation in attempted suicide by deliberate self poisoning 31
Nociceptin/Orphanin FQ and its receptor - Potential targets for pain therapy? 31
Structure-activity relationship study on Tyr9 of urotensin-II(4-11): identification of a partial agonist of the UT receptor 31
Further studies on the pharmacological features of the nociceptin/orphanin FQ receptor ligand ZP120 31
The paraventricular nucleus of the hypothalamus is a neuroanatomical substrate for the inhibition of palatable food intake by neuropeptide S 31
NOCICEPTIN RECEPTOR ACTIVATION INHIBITS TACHYNERGIC NON ADRENERGIC NON CHOLINERGIC CONTRACTION OF GUINEA PIG ISOLATED BRONCHUS 31
Approval of oliceridine (TRV130) for intravenous use in moderate to severe pain in adults 31
NOP receptor pharmacological profile – A dynamic mass redistribution study 31
Structure-activity study at positions 3 and 4 of human neuropeptide S 31
Long-lasting antinociceptive spinal effects in primates of the novel nociceptin/orphanin FQ receptor agonist UFP-112 31
Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68) 31
Further studies on nociceptin-related peptides: Discovery of a new chemical template with antagonist activity on the nociceptin receptor 31
N- and C-terminal modifications of nociceptin/orphanin FQ generate highly potent NOP receptor ligands 31
[(pF)Phe4,Arg14,Lys15]N/OFQ-NH2 (UFP-102), a highly potent and selective agonist of the nociceptin/orphanin FQ receptor 31
Binding of the novel radioligand [(3)H]UFP-101 to recombinant human and native rat nociceptin/orphanin FQ receptors 31
[Nphe(1),Arg(14),Lys(15)]N/OFQ-NH2 is a competitive antagonist of NOP receptors in the periaqueductal gray 31
Synthesis and Structure–Activity Relationships of Triazaspirodecanone Derivatives as Nociceptin/Orphanin FQ Receptor Ligands 31
Behavioural phenotypic characterization of CD-1 mice lacking the neuropeptide S receptor 31
Pharmacological Investigations of N-Substituent Variation in Morphine and Oxymorphone: Opioid Receptor Binding, Signaling and Antinociceptive Activity 31
Pharmacology of endothelins: vascular preparations for studying ETA and ETB receptors 31
In vitro and in vivo studies on UFP-112, a novel potent and long lasting agonist selective for the nociceptin/orphanin FQ receptor 30
The effects of neuropeptide S on general anesthesia in rats 30
In vitro and in vivo pharmacological characterization of the novel neuropeptide S receptor ligands QA1 and PI1 30
Synthesis, enantiomeric separation and docking studies of spiropiperidine analogues as ligands of the nociceptin/orphanin FQ receptor 30
Lithium attenuates behavioral and biochemical effects of neuropeptide S in mice 30
Synthesis, biological evaluation and structural analysis of novel peripherally active morphiceptin analogs 30
UFP-112 a Potent and Long-Lasting Agonist Selective for the Nociceptin/Orphanin FQ Receptor 30
Nociceptin/orphanin FQ (N/OFQ) modulates immunopathology and airway hyperresponsiveness representing a novel target for the treatment of asthma 30
Pharmacological characterization of the bifunctional opioid ligand H-Dmt-Tic-Gly-NH-Bzl (UFP-505) 30
Synthesis, biological evaluation and docking studies of a novel class of sulfur-bridged diazabicyclo[3.3.1]nonanes 30
Plant-derived peptides rubiscolin-6, soymorphin-6 and their c-terminal amide derivatives: Pharmacokinetic properties and biological activity 30
Human vascular kinin receptors of the B-2 type characterized by radioligand binding 30
Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist Compound 24 30
Blockade of nociceptin/orphanin FQ signaling facilitates an active copying strategy due to acute and repeated stressful stimuli in mice 30
Totale 3.580
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Categoria #
all - tutte 58.601
article - articoli 55.897
book - libri 123
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 566
selected - selezionate 0
volume - volumi 842
Totale 116.029
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201910 0 0 0 0 0 0 0 0 0 0 4 6
2019/202028 2 1 0 1 3 2 2 3 5 4 5 0
2020/20212.147 2 3 1 3 1 0 0 2 846 915 76 298
2021/20225.534 146 1.519 395 274 252 73 430 479 264 43 615 1.044
2022/20231.017 616 38 15 30 57 75 11 38 55 9 26 47
2023/2024395 2 48 65 63 59 54 55 15 13 16 5 0
Totale 9.153