CALO', GIROLAMO
 Distribuzione geografica
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Continente #
NA - Nord America 11.433
AS - Asia 7.563
EU - Europa 4.332
AF - Africa 2.871
SA - Sud America 2.309
OC - Oceania 283
Continente sconosciuto - Info sul continente non disponibili 128
Totale 28.919
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Nazione #
US - Stati Uniti d'America 10.188
SG - Singapore 2.274
HK - Hong Kong 1.735
BR - Brasile 1.397
VN - Vietnam 743
FR - Francia 458
CN - Cina 361
RU - Federazione Russa 326
IT - Italia 310
PL - Polonia 299
FI - Finlandia 245
BJ - Benin 205
DE - Germania 187
AR - Argentina 159
IE - Irlanda 159
GB - Regno Unito 155
SE - Svezia 125
ID - Indonesia 114
EC - Ecuador 112
NL - Olanda 110
CO - Colombia 107
AO - Angola 105
KG - Kirghizistan 104
AT - Austria 101
MX - Messico 99
TR - Turchia 96
IQ - Iraq 95
PE - Perù 95
UA - Ucraina 93
ZA - Sudafrica 90
IN - India 89
PY - Paraguay 87
AE - Emirati Arabi Uniti 86
DZ - Algeria 86
SA - Arabia Saudita 85
KR - Corea 84
UZ - Uzbekistan 83
CL - Cile 82
CV - Capo Verde 82
LU - Lussemburgo 82
CI - Costa d'Avorio 81
IS - Islanda 81
PK - Pakistan 80
AL - Albania 79
MU - Mauritius 79
UY - Uruguay 78
AM - Armenia 77
EG - Egitto 77
ZW - Zimbabwe 77
LC - Santa Lucia 76
MG - Madagascar 76
MR - Mauritania 76
MY - Malesia 76
NO - Norvegia 76
SI - Slovenia 76
ES - Italia 75
HU - Ungheria 75
LV - Lettonia 75
PS - Palestinian Territory 75
CM - Camerun 74
KZ - Kazakistan 74
ME - Montenegro 74
CZ - Repubblica Ceca 73
LB - Libano 73
NE - Niger 73
RW - Ruanda 73
GA - Gabon 72
GH - Ghana 72
BB - Barbados 71
KH - Cambogia 71
MZ - Mozambico 71
NI - Nicaragua 71
VE - Venezuela 71
AZ - Azerbaigian 70
BA - Bosnia-Erzegovina 70
CG - Congo 70
DK - Danimarca 70
DO - Repubblica Dominicana 70
HN - Honduras 70
CW - ???statistics.table.value.countryCode.CW??? 69
GN - Guinea 69
TN - Tunisia 69
BW - Botswana 68
GT - Guatemala 68
PT - Portogallo 68
YT - Mayotte 68
BF - Burkina Faso 67
BG - Bulgaria 67
RE - Reunion 67
RS - Serbia 67
UG - Uganda 67
JM - Giamaica 66
LY - Libia 66
MK - Macedonia 66
NP - Nepal 66
BZ - Belize 65
CH - Svizzera 65
TW - Taiwan 65
JP - Giappone 64
PH - Filippine 64
Totale 25.792
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Città #
Fairfield 2.184
Hong Kong 1.680
Singapore 1.237
Ashburn 745
Woodbridge 650
Cambridge 631
Houston 604
Santa Clara 578
San Diego 499
Seattle 465
Boardman 403
Medford 388
Princeton 388
Wilmington 293
Des Moines 289
Dong Ket 278
Bytom 219
Ann Arbor 197
Cotonou 191
Ho Chi Minh City 183
Helsinki 182
Beijing 148
Dublin 142
Chandler 140
Roxbury 115
São Paulo 107
Hanoi 101
Los Angeles 101
Bishkek 92
Luanda 84
Tashkent 78
Chicago 77
Abidjan 75
Castries 74
Praia 71
Vienna 71
Managua 70
Harare 69
Kigali 69
Nouakchott 69
Antananarivo 68
Baku 68
Bridgetown 68
Conakry 67
Kampala 65
Montevideo 65
Phnom Penh 65
Accra 63
Libreville 62
Reykjavik 62
Riga 62
Willemstad 61
Yerevan 61
Dakar 60
Nassau 59
Niamey 59
Amman 58
Podgorica 58
Lima 57
Lusaka 57
Ulan Bator 57
Nairobi 56
Ouagadougou 56
Maputo 54
Padova 54
Tripoli 54
Panama City 53
Rio de Janeiro 53
Bamako 51
Dushanbe 51
Gaborone 51
Andorra la Vella 49
Kingstown 49
Noumea 49
San José 49
Vientiane 48
Kinshasa 46
Mamoudzou 46
Tirana 46
Cayenne 45
Dar es Salaam 45
Tallinn 45
Papeete 44
Quito 43
Sanaa 43
Sofia 43
Pristina 42
Guatemala City 41
Skopje 41
Lilongwe 40
Salt Lake City 40
Kingston 39
London 39
Luxembourg 39
Tbilisi 39
Abu Dhabi 37
Guayaquil 37
Havana 37
Kuala Lumpur 37
Addis Ababa 36
Totale 17.106
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Nome #
1,4-Dioxolane-triazaspirodecanone derivatives as nociceptin/orphanin FQ receptor ligands 219
Hyaluronic Acid Induces Activation of the κ-Opioid Receptor 210
Acute and chronic antiparkinsonian effects of the novel nociceptin/orphanin FQ receptor antagonist NiK-21273 in comparison with SB-612111 127
In vitro and in vivo pharmaco-dynamic study of the novel fentanyl derivatives: Acrylfentanyl, Ocfentanyl and Furanylfentanyl 120
Pharmacological profile of nociceptin/orphanin FQ receptors interacting with G-proteins and β-arrestins 2 115
In vitro and in vivo pharmacological characterization of nociceptin/orphanin FQ tetrabranched derivatives 113
A Multi-Angle Approach to Predict Peptide-GPCR Complexes: The N/OFQ-NOP System as a Successful AlphaFold Application Case Study 111
(2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist 111
A simple method for electrical field stimulation of cultured granule cells 111
Novel Mixed NOP/Opioid Receptor Peptide Agonists 109
Pharmacological Assays for Investigating the NOP Receptor 107
[D-Pen(p-tBuBzl)5]NPS, a novel ligand for the neuropeptide S receptor: structure activity and pharmacological studies 106
Excitatory amino acids (EAAs) stimulate phosphatidylinositol turnover in adult rat striatal slices: interaction between NMDA and EAA metabotropic receptors 103
Modulation of Drosophila suzukii type 1 tyramine receptor (DsTAR1) by monoterpenes: a potential new target for next generation biopesticides 102
In vitro functional characterization of novel nociceptin/orphanin FQ receptor agonists in recombinant and native preparations 102
A novel and facile synthesis of tetra branched derivatives of nociceptin/orphanin FQ 101
Nociceptin Modulates Bronchoconstriction Induced by Sensory Nerve Activation in Mouse Lung 101
Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68) 101
N- and C-terminal modifications of nociceptin/orphanin FQ generate highly potent NOP receptor ligands 101
In vitro pharmacological characterization of a novel unbiased NOP receptor-selective nonpeptide agonist AT-403 101
The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor 101
Noradrenergic modulation of gamma-aminobutyric acid outflow from the human cerebral cortex 100
In vitro pharmacological characterization of growth hormone secretagogue receptor ligands using the dynamic mass redistribution and calcium mobilization assays 100
Functional Selectivity Does Not Predict Antinociceptive/Locomotor Impairing Potencies of NOP Receptor Agonists 99
Circadian variation in attempted suicide by deliberate self-poisoning 98
Stress induces reinstatement of extinguished cocaine conditioned place preference by a sequential signaling via neuropeptide S, orexin, and endocannabinoid 98
A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism 98
Pharmacology of Kappa Opioid Receptors: Novel Assays and Ligands 98
Effects of Stress Exposure to Pain Perception in Pre-Clinical Studies: Focus on the Nociceptin/Orphanin FQ-NOP Receptor System 97
Biased versus Partial Agonism in the Search for Safer Opioid Analgesics 97
Hypothalamic neuropeptide S receptor blockade decreases discriminative cue-induced reinstatement of cocaine seeking in the rat 96
In vitro and in vivo pharmacological characterization of a neuropeptide S tetrabranched derivative 96
Detailed in vitro pharmacological characterization of the clinically viable nociceptin/orphanin FQ peptide receptor antagonist BTRX-246040 95
Pharmacological Investigations of N-Substituent Variation in Morphine and Oxymorphone: Opioid Receptor Binding, Signaling and Antinociceptive Activity 95
Structure-Activity Relationship Studies on Oxazolo[3,4-a]pyrazine Derivatives Leading to the Discovery of a Novel Neuropeptide S Receptor Antagonist with Potent In Vivo Activity 95
Pharmacological characterization of endomorphin-2-based cyclic pentapeptides with methylated phenylalanine residues 95
[(t)Bu-d-Gly(5)]NPS, a pure and potent antagonist of the neuropeptide S receptor: In vitro and in vivo studies 94
Beta-arrestin 2 rather than G protein efficacy determines the anxiolytic- versus antidepressant-like effects of nociceptin/orphanin FQ receptor ligands 94
NOP receptor pharmacological profile – A dynamic mass redistribution study 94
Pharmacological characterization of tachykinin tetrabranched derivatives 94
A staged screening of registered drugs highlights remyelinating drug candidates for clinical trials 94
[(pF)Phe4,Arg14,Lys15]N/OFQ-NH2 (UFP-102), a highly potent and selective agonist of the nociceptin/orphanin FQ receptor 94
Anxiolytic- and panicolytic-like effects of Neuropeptide S in the mouse elevated T-maze 94
In vitro and in vivo pharmacological characterization of the neuropeptide S receptor antagonist [D-Cys(tBu)5]NPS 93
Further studies on the pharmacological features of the nociceptin/orphanin FQ receptor ligand ZP120 93
Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonist 93
Nociceptin/Orphanin FQ Receptor Structure, Signaling, Ligands, Functions, and Interactions with Opioid Systems 93
Long-lasting antinociceptive spinal effects in primates of the novel nociceptin/orphanin FQ receptor agonist UFP-112 93
In vitro and in vivo pharmacological characterization of Pronetupitant, a prodrug of the neurokinin 1 receptor antagonist Netupitant 93
[Dmt(1) ]N/OFQ(1-13)-NH(2) , a potent nociceptin/orphanin FQ and opioid receptor universal agonist 93
Characterization of Halyomorpha halys TAR1 reveals its involvement in (E)-2-decenal pheromone perception 93
Preclinical effects of cannabidiol in an experimental model of migraine 92
Cyclic mu-opioid receptor ligands containing multiple N-methylated amino acid residues 92
The concise guide to pharmacology 2019/20: G protein-coupled receptors 92
Further studies on the pharmacological profile of the neuropeptide S receptor antagonist SHA 68 91
[(pF)Phe(4), Arg(14), Lys(15)]N/OFQ-NH2 (UFP-102), a highly potent and selective agonist of the nociceptin/orphanin FQ receptor 91
Effect of neuropeptide S receptor antagonists and partial agonists on palatable food consumption in the rat 91
Characterisation of the novel mixed Mu-NOP peptide ligand dermorphin-N/OFQ (DeNo) 91
Pharmacological characterization of the bifunctional opioid ligand H-Dmt-Tic-Gly-NH-Bzl (UFP-505) 91
Activation of the nociceptin/orphanin FQ receptor reduces bronchoconstriction and microvascular leakage in a rabbit model of gastroesophageal reflux 91
In vitro and in vivo pharmacological characterization of the synthetic opioid MT-45 91
Pharmacological characterization of naloxegol: In vitro and in vivo studies 91
Fluorescent opioid receptor ligands as tools to study opioid receptor function 91
Circadian variation in attempted suicide by deliberate self poisoning 90
Comparative biochemical and pharmacological characterization of a novel, NOP receptor selective hexapeptide, Ac-RYYRIR-ol 90
Synthesis, enantiomeric separation and docking studies of spiropiperidine analogues as ligands of the nociceptin/orphanin FQ receptor 90
1999, Pharmacological characterisation of the first non-peptide bradykinin B2 receptor agonist FR 190997: an in vitro study on human, rabbit and pig vascular B2 receptors 90
Nociceptin/orphanin FQ (N/OFQ) modulates immunopathology and airway hyperresponsiveness representing a novel target for the treatment of asthma 90
Nociceptin/orphanin FQ and urinary bladder 89
Spinal antinociceptive effects of the novel NOP receptor agonist PWT2-nociceptin/orphanin FQ in mice and monkeys 89
The effects of neuropeptide S on general anesthesia in rats 89
Acute thrombosis of abdominal aorta in a petient under warfarin treatment 89
Desensitisation of native and recombinant human urotensin-II receptors 89
Further studies at neuropeptide s position 5: discovery of novel neuropeptide S receptor antagonists 89
[Nphe(1),Arg(14),Lys(15)]N/OFQ-NH2 is a competitive antagonist of NOP receptors in the periaqueductal gray 89
The NOP antagonist BTRX-246040 increases stress resilience in mice without affecting adult neurogenesis in the hippocampus 89
NOP-Targeted Peptide Ligands 88
Medicinal Chemistry, Pharmacology, and Biological Actions of Peptide Ligands Selective for the Nociceptin/Orphanin FQ Receptor 88
Nociceptin/orphanin FQ receptor knockout rats: in vitro and in vivo studies 88
Approval of oliceridine (TRV130) for intravenous use in moderate to severe pain in adults 88
Structure-activity study at positions 3 and 4 of human neuropeptide S 88
Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic 88
MOP and NOP receptor interaction: Studies with a dual expression system and bivalent peptide ligands 88
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors 87
Effects of neuropeptide S on seizures and oxidative damage induced by pentylenetetrazole in mice 87
UFP-112 a Potent and Long-Lasting Agonist Selective for the Nociceptin/Orphanin FQ Receptor 87
The Nociceptin/Orphanin FQ Receptor Antagonist UFP-101 Reduces Microvascular Inflammation to Lipopolysaccharide In Vivo. 87
Electrocardiographic alterations as a result of acute intoxication with fluvoxamine and pipamperone 86
Neuropeptide S stimulates human monocyte chemotaxis via NPS receptor activation 86
Urotensin II evokes neurotransmitter release from rat cerebrocortical slices 86
Pharmacological studies on the NOP and opioid receptor agonist PWT2-[Dmt(1)]N/OFQ(1-13) 86
Actual concept of "probiotics": is it more functional to science or business? 86
Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist Compound 24 86
AGONISTI PIENI E PARZIALI ED ANTAGONISTI DEL RECETTORE PER NOCICETTINA/ORFANINA FQ AD ELEVATA POTENZA” 86
In Vitro and In Vivo Pharmaco-Toxicological Characterization of 1-Cyclohexyl-x-methoxybenzene Derivatives in Mice: Comparison with Tramadol and PCP 86
The paraventricular nucleus of the hypothalamus is a neuroanatomical substrate for the inhibition of palatable food intake by neuropeptide S 85
AMPA receptor activation regulates the glutamate metabotropic receptor stimulated phosphatidylinositol turnover in human cerebral cortex slices 85
Modulation of Silent and Constitutively Active Nociceptin/Orphanin FQ Receptors by Potent Receptor Antagonists and Na+ Ions in Rat Sympathetic Neurons 85
Human vascular kinin receptors of the B-2 type characterized by radioligand binding 85
Evaluation of [Cys(ATTO 488)8]Dermorphin-NH2 as a novel tool for the study of μ-opioid peptide receptors 85
Totale 9.665
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Categoria #
all - tutte 107.273
article - articoli 100.667
book - libri 246
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 1.526
selected - selezionate 0
volume - volumi 1.745
Totale 211.457
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20212.137 0 0 0 0 1 0 0 2 845 915 76 298
2021/20225.526 146 1.516 395 273 252 73 430 478 264 43 615 1.041
2022/20231.016 615 38 15 30 57 75 11 38 55 9 26 47
2023/2024793 2 48 65 63 59 54 55 15 13 16 97 306
2024/20256.761 10 667 511 35 900 103 260 531 863 395 1.050 1.436
2025/202613.051 549 2.696 4.125 5.256 425 0 0 0 0 0 0 0
Totale 29.353