Distribuzione geografica
Continente #
NA - Nord America 12.946
EU - Europa 1.343
AS - Asia 908
Continente sconosciuto - Info sul continente non disponibili 7
SA - Sud America 4
AF - Africa 2
OC - Oceania 2
Totale 15.212
Nazione #
US - Stati Uniti d'America 12.939
CN - Cina 708
FI - Finlandia 307
IT - Italia 234
DE - Germania 231
SE - Svezia 211
UA - Ucraina 163
VN - Vietnam 147
GB - Regno Unito 110
FR - Francia 32
IN - India 32
IE - Irlanda 25
JP - Giappone 10
NL - Olanda 8
RO - Romania 8
CA - Canada 7
EU - Europa 7
HK - Hong Kong 3
RU - Federazione Russa 3
AT - Austria 2
AU - Australia 2
BR - Brasile 2
CH - Svizzera 2
KR - Corea 2
NG - Nigeria 2
PE - Perù 2
SI - Slovenia 2
BG - Bulgaria 1
HR - Croazia 1
HU - Ungheria 1
IR - Iran 1
KZ - Kazakistan 1
NO - Norvegia 1
PL - Polonia 1
SG - Singapore 1
TJ - Tagikistan 1
TR - Turchia 1
TW - Taiwan 1
Totale 15.212
Città #
Fairfield 2.014
Woodbridge 1.546
Chandler 1.175
Ann Arbor 1.173
Houston 1.144
Ashburn 825
Seattle 738
Cambridge 726
Jacksonville 725
Wilmington 723
Princeton 321
Beijing 196
San Diego 190
Des Moines 148
Dong Ket 147
Nanjing 130
Helsinki 124
Roxbury 109
Medford 108
Padova 108
Boardman 105
Shenyang 50
Nanchang 42
New York 39
Hebei 32
Guangzhou 29
Norwalk 28
Tianjin 27
Dublin 25
Jiaxing 25
London 24
Falls Church 22
Jinan 19
Changsha 18
Dearborn 17
Milan 16
Kharkiv 14
Redwood City 14
Nürnberg 11
Tappahannock 11
Zhengzhou 11
Borås 9
Hounslow 9
San Francisco 9
Taizhou 9
Hefei 8
Indiana 8
Paris 8
Haikou 7
Ningbo 7
Detroit 6
Kilburn 6
Kunming 6
Lanzhou 6
Munich 6
Rockville 6
Shanghai 6
Chicago 5
Chieti 5
Pune 5
Usuki 5
Washington 5
Harbin 4
Lappeenranta 4
Acton 3
Auburn Hills 3
Berlin 3
Denver 3
Dundee 3
Frankfurt am Main 3
Hangzhou 3
Las Vegas 3
Leawood 3
Perugia 3
Prescot 3
Taiyuan 3
Timisoara 3
Toronto 3
Troy 3
Wandsworth 3
Aprilia 2
Atlanta 2
Baotou 2
Belluno 2
Bologna 2
Buffalo 2
Casier 2
Columbia 2
Edinburgh 2
Fuzhou 2
Groningen 2
Horia 2
Islington 2
Lausanne 2
Lima 2
Matsuyama 2
Münster 2
Phoenix 2
Romainville 2
Rome 2
Totale 13.186
Nome #
Characterization of a plant glutamate receptor activity 164
A V1143F mutation in the neuronal-enriched isoform 2 of the PMCA pump is linked with ataxia 160
Chemical Synthesis and Structural Characterization of the RGD-protein Decorsin: a Potent Inhibitor of Platelet Aggregation 139
Protein kinase CK2 phosphorylates and upregulates Akt/PKB 139
Phosphorylation and activation of the atypical kinase p53-related protein kinase (PRPK) by Akt/PKB 133
A BARF1-specific mAb as a new immunotherapeutic tool for the management of EBV-related tumors 131
Milk-derived bioactive peptides protect against oxidative stress in a Caco-2 cell model 129
Structure-function analysis of yeast piD261/Bud32, an atypical protein kinase essential for normal cell life. 127
CK2 activity is modulated by growth rate in Saccharomyces cerevisiae 126
Structural and Antimicrobial Features of Peptides Related to Myticin C, a Special Defense Molecule from the Mediterranean Mussel Mytilus galloprovincialis 126
Chemical synthesis of the RGD-protein decorsin: Pro-Ala replacement reduces protein thermostability. 125
A plant oncogene as a phosphatase 125
Basic residues in the 74-83 and 191-198 segments of protein kinase CK2 catalytic subunit are implicated in negative but not in positive regulation by the beta-subunit 124
Aurora-A site specificity: a study with synthetic peptide substrates 123
Cell surface nucleolin interacts with and internalizes Bothrops asper Lys49 phospholipase A2and mediates its toxic activity 121
Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels 119
Sic1 is phosphorylated by CK2 on Ser201 in budding yeast cells 119
Gene therapy of Hunter syndrome: Evaluation of the efficiency of muscle electro genetransfer for the production and release of recombinant iduronate-2-sulfatase (IDS) 119
Site specificity of p72syk protein tyrosine kinase. Efficient phosphorylation of motifs recognized by Src homology 2 domains of the Src family 116
Interaction between the SH3 domain of Src family kinases and the proline-rich motif of HTLV-1 p13: a novel mechanism underlying delivery of Src family kinases to mitochondria. 116
A "SYDE" effect of hierarchical phosphorylation: possible relevance to the cystic fibrosis basic defect. 113
Insight into antioxidant properties of milk-derived bioactive peptides in vitro and in a cellular model 113
Heterogeneity of CK2 phosphorylation sites in the NS5A protein of different hepatitis C virus genotypes. 112
Conformational Stability of Neuroglobin Helix F: Possible Effects on the Folding Pathway within the Globin Family 111
GLP-1 cleavage product reverses persistent ROS generation after transient hyperglycemia by disrupting an ROS-generating feedback loop 111
Acidophilic character of yeast piD261/Bud32, a putative ancestor of eukaryotic protein kinases 111
Possible implication of the golgi apparatus casein kinase in the phosphorylation of vesicle docking protein p115 ser-940: a study with peptide substrates 110
Phosphorylation of cystic fibrosis transmembrane conductance regulator (CFTR) serine-511 by the combined action of tyrosine kinases and CK2: the implication of tyrosine-512 and phenylalanine-508 110
Antamanide, a Derivative of Amanita phalloides, is a Novel Inhibitor of the Mitochondrial Permeability Transition Pore. 110
Protein kinase CK2 modulates HSJ1 function through phosphorylation of the UIM2 domain 108
Chimeric peptides as modulators of CK2-dependent signaling: Mechanism of action and off-target effects 108
Specificity of T-cell protein tyrosine phosphatase toward phosphorylated synthetic peptides. 106
Enzyme mimics complexing Cu (II)ion: structure-function relationships 105
Synthetic peptides including acidic clusters as substrates of yeast casein kinase-2. 105
405 HCV NS5A phosphorylation by CK2 is genotype dependent 104
Mutational analysis of residues implicated in the interaction between protein kinase CK2 and peptide substrates 104
Isoform specific phosphorylation of p53 by protein kinase CK1 104
Functional homology between yeast piD261/Bud32 and human PRPK: both phosphorylate p53 and PRPK partially complements piD261/Bud32 deficiency 103
An analysis of the substrate specificity of insulin-stimulated protein kinase-1, a mammalian homologue of S6 kinase-II. 103
Proapoptotic effect of hepatitis C virus CORE protein in transiently transfected cells is enhanced by nuclear localization and is dependent on PKR activation 103
Superiority of PLK-2 as α-synuclein phosphorylating agent relies on unique specificity determinants. 102
Unique features of HIV-1 Rev protein phosphorylation by protein kinase CK2 ('casein kinase-2') 102
Spontaneous autophosphorylation of Lyn tyrosine kinase at both its activation segment and C-terminal tail confers altered substrate specificity 102
Targeted Polymeric Nanoparticles for Brain Delivery of High Molecular Weight Molecules in Lysosomal Storage Disorders 102
Fam20C-mediated phosphorylation of osteopontin is critical for its secretion but dispensable for its action as a cytokine in the activation of hepatic stellate cells in liver fibrogenesis 102
CK2 regulates in vitro the activity of the yeast cyclin-dependent kinase inhibitor Sic1 101
Cystic fibrosis transmembrane regulator fragments with the Phe508 deletion exert a dual allosteric control over the master kinase CK2 100
A multifunctional network of basic residues confers unique propertiers to protein kinase CK2 100
DPP4 inhibitor and pharmaceutical application thereof 98
The ataxia related G1107D mutation of the plasma membrane Ca2+ ATPase isoform 3 affects its interplay with calmodulin and the autoinhibition process. 98
Reduction of GAG storage in MPS II mouse model following implantation of encapsulated recombinant myoblasts 97
The first armadillo repeat is involved in the recognition and regulation of beta-catenin phosphorylation by protein kinase CK1 97
Spleen protein tyrosine kinases TPK-IIB and CSK display different immunoreactivity and opposite specificities toward c-src-derived peptides. 96
Specific stimulation of c-Fgr kinase by tyrosine-phosphorylated (poly)peptides--possible implication in the sequential mode of protein phosphorylation. 95
Different specificities of spleen tyrosine protein kinases for synthetic peptide substrates. 95
Conformational changes upon calcium binding and phosphorylation in a synthetic fragment of calmodulin. 94
Modulation of mitochondrial K(+) permeability and reactive oxygen species production by the p13 protein of human T-cell leukemia virus type 1 93
Effective genetic vaccination with a widely shared endogenous retroviral tumor antigen requires CD40 stimulation during tumor rejection phase. 93
MBNL142 and MBNL143 gene isoforms, overexpressed in DM1-patient muscle, encode for nuclear proteins interacting with Src family kinases 93
Spectroscopic studies of the mitochondrial targeting signal of the HTLV-1 P13II protein: a-helix formation and aggregation in lipophilic environments 92
Phosphorylation of calmodulin fragments by protein kinase CK2. Mechanistic aspects and structural consequences 92
Discrimination between the activity of protein kinase CK2 holoenzyme and its catalytic subunits 91
Dual localization of plant glutamate receptor AtGLR3.4 to plastids and plasmamembrane 91
Conformational properties of the SDS-bound state of alfa-synuclein probed by limited proteolysis: Unexpected rigidity of the acidic C-terminal tail 90
TAT-mediated aequorin transduction: an alternative approach for effective calcium measurements in plant cells 90
Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels 89
The synaptotagmin juxtamembrane domain is involved in neuroexocytosis 89
Cx32 hemichannel opening by cytosolic Ca2+is inhibited by the R220X mutation that causes Charcot-Marie-Tooth disease 89
Effects of human T-cell leukemia virus type 1 (HTLV-1) p13 on mitochondrial K+ permeability: A new member of the viroporin family? 88
Milk-derived bioactive peptides exhibit antioxidant activity through the Keap1-Nrf2 signaling pathway 88
Biochemical evidence that Saccharomyces cerevisiae YGR262c gene, required for normal growth, encodes a novel Ser/Thr-specific protein kinase 86
Phosphotyrosine specifies the phosphorylation by protein kinase CK2 of a peptide reproducing the activation loop of the insulin receptor protein tyrosine kinase. 84
Chemical dissection of the APC repeat 3 multistep phosphorylation by the concerted action of protein kinases CK1 and GSK3 84
Mapping of the Neisseria meningitidis NadA Cell-Binding Site: Relevance of Predicted alpha-Helices in the NH2-Terminal and Dimeric Coiled-Coil Regions 84
Ser/Thr phosphorylation of hematopoietic specific protein 1 (HS1) - Implication of protein kinase CK2 83
Molecular features underlying the sequential phosphorylation of HS1 protein and its association with c-Fgr protein-tyrosine kinase. 83
A noncanonical sequence phosphorylated by casein kinase 1 in beta-catenin may play a role in casein kinase 1 targeting of important signaling proteins 83
Cx32 hemichannel opening by cytosolic Ca2+ is inhibited by the R220X mutation that causes Charcot-Marie-Tooth disease 83
Variability in the CK2 dependent phosphorylation of NS5A among HCV genotypes: Possible implications in caspases cleavage 82
Increased serum resistin in adults with prader-willi syndrome is related to obesity and not to insulin resistance 81
Unique substrate specificity of anaplastic lymphoma kinase (ALK): development of phosphoacceptor peptides for the assay of ALK activity. 81
Myotonic dystrophy protein kinase (DMPK) prevents ROS-induced cell death by assembling a hexokinase II-Src complex on the mitochondrial surface 81
Effect of polycation peptides on mitochondrial permeability transition. 79
Design, Synthesis, and Biological Activity of Urea Derivatives as Anaplastic Lymphoma Kinase Inhibitors 79
Identification of New Peptides from Fermented Milk Showing Antioxidant Properties: Mechanism of Action 79
The Golgi ‘casein kinase’ Fam20C is a genuine ‘phosvitin kinase’ and phosphorylates polyserine stretches devoid of the canonical consensus 78
Screening inhibitors of anthrax lethal factor. 77
Design and synthesis of two new peptide substrates for the specific and sensitive monitoring of casein kinases-1 and -2. 77
Expression, purification, and inhibition of human RET tyrosine kinase 77
Cystic fibrosis transmembrane regulator fragments with the Phe508 deletion exert a dual allosteric control over the master kinase CK2. 77
Hexokinase 2 displacement from mitochondria‐associated membranes prompts Ca 2+ ‐dependent death of cancer cells 77
Selective effect of poly(lysine) on the enhancement of the lyn tyrosine protein kinase activity. Increased specificity toward src peptides. 77
A Modified KESTREL Search Reveals a Basophilic Substrate Consensus for the Saccharomyces cerevisiae Npr1 Protein Kinase 76
Golgi apparatus mammary gland casein kinase: monitoring by a specific peptide substrate and definition of specificity determinants 76
A Naturally Occurring Antibody Fragment Neutralizes Infectivity of Diverse Infectious Agents 76
Substrate recognition by casein kinase-II: The role of histidine-160 75
Multiple Phosphorylation Sites at the C-terminus Regulate Nuclear Import of HCMV DNA Polymerase Processivity Factor ppUL44. 75
Inhibition of macroautophagy and proteolysis in the isolated rat hepatocyte by a nontransportable derivative of the multiple antigen peptide Leu8-Lys4-Lys2-Lys-βAla 74
Encapsulated engineered myoblasts can cure Hurler syndrome: preclinical experiments in the mouse model. 74
Totale 9.970
Categoria #
all - tutte 46.632
article - articoli 43.756
book - libri 247
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 292
selected - selezionate 0
volume - volumi 167
Totale 91.094

Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20191.301 0 0 0 0 0 0 0 107 19 251 500 424
2019/20203.116 464 102 42 190 312 250 312 387 331 367 232 127
2020/20212.378 114 141 87 221 129 270 73 213 390 214 252 274
2021/20222.780 49 315 428 213 127 143 109 337 117 42 336 564
2022/20232.288 423 252 35 304 365 333 2 159 257 27 91 40
2023/2024756 59 178 118 73 102 97 86 43 0 0 0 0
Totale 15.322