MALFACINI, DAVIDE
MALFACINI, DAVIDE
Dipartimento di Scienze del Farmaco - DSF
(L)-Monomethyl Tyrosine (Mmt): New Synthetic Strategy via Bulky 'Forced-Traceless' Regioselective Pd-Catalyzed C(sp2)-H Activation
2023 Illuminati, Davide; Trapella, Claudio; Zanirato, Vinicio; Guerrini, Remo; Albanese, Valentina; Sturaro, Chiara; Stragapede, Simona; Malfacini, Davide; Compagnin, Greta; Catani, Martina; Fantinati, Anna
1,4-Dioxolane-triazaspirodecanone derivatives as nociceptin/orphanin FQ receptor ligands
2014 Corrado, S.; Sorbi, C; Tait, A; Battisti, U. M.; Camarda, V.; Malfacini, D.; Calo', G.; Brasili, L.
[D-Pen(p-tBuBzl)5]NPS, a novel ligand for the neuropeptide S receptor: structure activity and pharmacological studies
2014 Ruzza, C.; del Zoppo, L.; Malfacini, D.; Pela’, M.; Trapella, C.; Grieco, P.; Salvadori, S.; Calo’, G.; Guerrini., R.
A novel and facile synthesis of tetra branched derivatives of nociceptin/orphanin FQ
2014 Guerrini, R; Marzola, E; Trapella, C; Pela', M; Molinari, S; Cerlesi, Mc; Malfacini, D; Rizzi, A; Salvadori, S; Calo', G.
Acute and chronic antiparkinsonian effects of the novel nociceptin/orphanin FQ receptor antagonist NiK-21273 in comparison with SB-612111
2013 Marti, Matteo; Mela, Flora; Budri, Mirco; Volta, Mattia; Malfacini, Davide; Molinari, Stefano; N. T., Zaveri; S., Ronzoni; P., Petrillo; Calo', Girolamo; Morari, Michele
Beta-arrestin 2 rather than G protein efficacy determines the anxiolytic- versus antidepressant-like effects of nociceptin/orphanin FQ receptor ligands
2016 Asth, L; Ruzza, Chiara; Malfacini, Davide; Medeiros, I; Guerrini, Remo; Zaveri, N. T; Gavioli, E. C; Calo', Girolamo
Characterisation of the novel mixed Mu-NOP peptide ligand dermorphin-N/OFQ (DeNo)
2016 Bird, Mark F.; Camilla Cerlesi, Maria; Brown, Mark; Malfacini, Davide; Vezzi, Vanessa; Molinari, Paola; Micheli, Laura; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Guerrini, Remo; Calo', Girolamo; Lambert, David G.
Exploring pharmacological activities and signaling of morphinans substituted in position 6 as potent agonists interacting with the μ opioid receptor
2014 Ben Haddou, Tanila; Malfacini, Davide; Calo', Girolamo; Mario, D Aceto; Louis, S Harris; John, R Traynor; Coop, Andrew; Schmidhammer, Helmut; Spetea, Mariana
Functional Selectivity Does Not Predict Antinociceptive/Locomotor Impairing Potencies of NOP Receptor Agonists
2021 Azevedo Neto, Joaquim; Ruzza, Chiara; Sturaro, Chiara; Malfacini, Davide; Pacifico, Salvatore; Zaveri, Nurulain T.; Calò, Girolamo
Functional selectivity of EM-2 analogs at the mu-opioid receptor
2023 Piekielna-Ciesielska, Justyna; Malfacini, Davide; Djeujo, Francine Medjiofack; Marconato, Chantal; Wtorek, Karol; Calo', Girolamo; Janecka, Anna
GPCR in Adipose Tissue Function-Focus on Lipolysis
2023 Malfacini, Davide; Pfeifer, Alexander
Heterologous Expression, Biosynthetic Studies, and Ecological Function of the Selective Gq-Signaling Inhibitor FR900359
2018 Crusemann, M.; Reher, R.; Schamari, I.; Brachmann, A. O.; Ohbayashi, T.; Kuschak, M.; Malfacini, D.; Seidinger, A.; Pinto-Carbo, M.; Richarz, R.; Reuter, T.; Kehraus, S.; Hallab, A.; Attwood, M.; Schioth, H. B.; Mergaert, P.; Kikuchi, Y.; Schaberle, T. F.; Kostenis, E.; Wenzel, D.; Muller, C. E.; Piel, J.; Carlier, A.; Eberl, L.; Konig, G. M.
In vitro and in vivo pharmaco-dynamic study of the novel fentanyl derivatives: Acrylfentanyl, Ocfentanyl and Furanylfentanyl
2022 Bilel, S.; Azevedo Neto, J.; Arfe, R.; Tirri, M.; Gaudio, R. M.; Fantinati, A.; Bernardi, T.; Boccuto, F.; Marchetti, B.; Corli, G.; Serpelloni, G.; De-Giorgio, F.; Malfacini, D.; Trapella, C.; Calo', G.; Marti, M.
In vitro and in vivo pharmacological characterization of a neuropeptide S tetrabranched derivative
2015 Ruzza, Chiara; Rizzi, Anna; Malfacini, Davide; Pulga, Alice; Pacifico, Salvatore; Salvadori, Severo; Trapella, Claudio; Reinscheid, Rainer K; Calo', Girolamo; Guerrini, Remo
In vitro and in vivo pharmacological characterization of nociceptin/orphanin FQ tetrabranched derivatives
2014 Rizzi, A; Malfacini, D; C Cerlesi, M; Ruzza, C; Marzola, E; F Bird, M; J Rowbotham, D; Salvadori, S; Guerrini, R; G Lambert, D; Calo, G
In vitro and in vivo pharmacological characterization of Pronetupitant, a prodrug of the neurokinin 1 receptor antagonist Netupitant
2015 Ruzza, Chiara; Rizzi, Anna; Malfacini, Davide; Molinari, Stefano; Giuliano, Claudio; Lovati, Emanuela; Pietra, Claudio; Calo, Girolamo
In vitro functional characterization of novel nociceptin/orphanin FQ receptor agonists in recombinant and native preparations
2016 Ferrari, Federica; Cerlesi Maria, Camilla; Malfacini, Davide; Asth, Laila; Gavioli Elaine, C; Journigan Blair, V; Kamakolanu Uma, Gayathri; Meyer Michael, E; Yasuda, Dennis; Polgar Willma, E; Rizzi, Anna; Guerrini, Remo; Ruzza, Chiara; Zaveri Nurulain, T; Calo, Girolamo
In vitro pharmacological characterization of a novel unbiased NOP receptor-selective nonpeptide agonist AT-403
2017 Ferrari, Federica; Malfacini, Davide; Journigan, Blair V.; Bird, Mark F.; Trapella, Claudio; Guerrini, Remo; Lambert, David G.; Calo', Girolamo; Zaveri, Nurulain T.
Lack of beta-arrestin signaling in the absence of active G proteins
2018 Grundmann, M.; Merten, N.; Malfacini, D.; Inoue, A.; Preis, P.; Simon, K.; Ruttiger, N.; Ziegler, N.; Benkel, T.; Schmitt, N. K.; Ishida, S.; Muller, I.; Reher, R.; Kawakami, K.; Inoue, A.; Rick, U.; Kuhl, T.; Imhof, D.; Aoki, J.; Konig, G. M.; Hoffmann, C.; Gomeza, J.; Wess, J.; Kostenis, E.
NOP receptor pharmacological profile – A dynamic mass redistribution study
2018 Malfacini, Davide; Simon, Katharina; Trapella, Claudio; Guerrini, Remo; Zaveri, Nurulain T.; Kostenis, Evi; Calo, Girolamo