In the past few years, miniaturized tissue-equivalent gas detectors (mini TEPCs) have been developed for application of microdosimetry in radiotherapy. These mini-TEPCs are characterised by millimetric dimensions. They are equipped neither with an internal calibration source nor with electric field tubes, which would properly define the sensitive volume hence the simulated site size. In spite of these lacks, mini TEPCs working in gas flow conditions have proven to be precise and reliable detectors. However, for future therapeutic plans including microdosimetric data, consistency between experimental and calculated data is important. Existing general-purpose Monte Carlo codes have proven to be very useful to calculate the energy deposition due to ionization in macroscopic targets, even in various complex radiation fields. However, theoretical models implemented in these codes for simulating electron transport and straggling are valid only for energies above a few keV. This restricts their applicability for simulating radiation transport at a micrometric level, where low-energy electrons play a dominant role. In this work, we calculate frequency distributions of deposited energy in a mini TEPC (with sizes equivalent to 1 and 2 μm) due to photons using the Monte Carlo code FLUKA. Comparisons between simulated and experimental data show a rather good agreement. Differences due to different FLUKA settings are discussed.

Monte Carlo simulation of mini TEPC microdosimetric spectra: influence of Low-Energy Electrons.

MORO, DAVIDE;DE NARDO, LAURA
2010

Abstract

In the past few years, miniaturized tissue-equivalent gas detectors (mini TEPCs) have been developed for application of microdosimetry in radiotherapy. These mini-TEPCs are characterised by millimetric dimensions. They are equipped neither with an internal calibration source nor with electric field tubes, which would properly define the sensitive volume hence the simulated site size. In spite of these lacks, mini TEPCs working in gas flow conditions have proven to be precise and reliable detectors. However, for future therapeutic plans including microdosimetric data, consistency between experimental and calculated data is important. Existing general-purpose Monte Carlo codes have proven to be very useful to calculate the energy deposition due to ionization in macroscopic targets, even in various complex radiation fields. However, theoretical models implemented in these codes for simulating electron transport and straggling are valid only for energies above a few keV. This restricts their applicability for simulating radiation transport at a micrometric level, where low-energy electrons play a dominant role. In this work, we calculate frequency distributions of deposited energy in a mini TEPC (with sizes equivalent to 1 and 2 μm) due to photons using the Monte Carlo code FLUKA. Comparisons between simulated and experimental data show a rather good agreement. Differences due to different FLUKA settings are discussed.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11577/2424071
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