OBJECTIVES: To identify the most significant variables in determining if candidates with past or current addictions can be considered for liver transplantation. METHODS: Data relating to 58 cases from January 2001 to December 2003 were collected and analyzed. RESULTS: The decisional algorithm identified by discriminant analysis is based on the following variables: the duration of remission, treatment adherence, and the presence of a valid help relationship. Candidates undergoing initial remission (up to 12 months) must demonstrate both adherence and affective support; those with over 5 years of remission, however, are considered sufficiently reliable. A positive judgment is significantly correlated to overall survival and clinical improvement even without transplantation. CONCLUSIONS: In toxicological evaluation, treatment adherence and the presence of a valid help relationship for patients in remission from addictions can improve the selection criteria for liver transplantation, making it more dependable.

Alcohol- and substance-dependent subjects: The correlated factors in qualifying for liver transplantation

GALLIMBERTI, LUIGI;ANGELI, PAOLO;VITALE, ALESSANDRO;CILLO, UMBERTO;GATTA, ANGELO;D'AMICO, DAVIDE
2007

Abstract

OBJECTIVES: To identify the most significant variables in determining if candidates with past or current addictions can be considered for liver transplantation. METHODS: Data relating to 58 cases from January 2001 to December 2003 were collected and analyzed. RESULTS: The decisional algorithm identified by discriminant analysis is based on the following variables: the duration of remission, treatment adherence, and the presence of a valid help relationship. Candidates undergoing initial remission (up to 12 months) must demonstrate both adherence and affective support; those with over 5 years of remission, however, are considered sufficiently reliable. A positive judgment is significantly correlated to overall survival and clinical improvement even without transplantation. CONCLUSIONS: In toxicological evaluation, treatment adherence and the presence of a valid help relationship for patients in remission from addictions can improve the selection criteria for liver transplantation, making it more dependable.
2007
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11577/2467315
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