Acute decompensation (AD) of cirrhosis is defined by the acute development of ascites, gastrointestinal hemorrhage, hepatic encephalopathy, infection or any combination of these, requiring hospitalization. The presence of organ failure(s) in patients with AD defines acute-on-chronic liver failure (ACLF), while their absence defines AD. We designed the PREDICT study, a European, prospective, observational study, to characterize the clinical course of AD and predict ACLF.

The PREDICT study uncovers three clinical courses in acutely decompensated cirrhosis with distinct pathophysiology

Papp, Maria;Caraceni, Paolo;Laleman, Wim;Gambino, Carmine;Gatti, Pietro;Piano, Salvatore;Pavesi, Marco;Montagnese, Sara;Bernardi, Mauro;Moreau, Richard;Angeli, Paolo;
2020

Abstract

Acute decompensation (AD) of cirrhosis is defined by the acute development of ascites, gastrointestinal hemorrhage, hepatic encephalopathy, infection or any combination of these, requiring hospitalization. The presence of organ failure(s) in patients with AD defines acute-on-chronic liver failure (ACLF), while their absence defines AD. We designed the PREDICT study, a European, prospective, observational study, to characterize the clinical course of AD and predict ACLF.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11577/3346368
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