Peripheral artery disease (PAD) is a severe complication of diabetes, characterized by defective traffic of hematopoietic stem/progenitor cells (HSPCs). We examined the hematopoietic versus non-hematopoietic role of p66Shc in regulating HSPC traffic and blood flow recovery after ischemia in diabetic mice.

Hematopoietic and non-hematopoietic p66Shc differentially regulates stem cell traffic and vascular response to ischemia in diabetes

Albiero, Mattia;D'Anna, Marianna;Bonora, Benedetta Maria;Zuccolotto, Gaia;Rosato, Antonio;Giorgio, Marco;Iori, Elisabetta;Avogaro, Angelo;Fadini, Gian Paolo
2021

Abstract

Peripheral artery disease (PAD) is a severe complication of diabetes, characterized by defective traffic of hematopoietic stem/progenitor cells (HSPCs). We examined the hematopoietic versus non-hematopoietic role of p66Shc in regulating HSPC traffic and blood flow recovery after ischemia in diabetic mice.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11577/3402345
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