Sfoglia per Autore
The dimeric form of hpv16 e6 is crucial to drive yap/taz upregulation through the targeting of hscrib
2021 Messa, L.; Celegato, M.; Bertagnin, C.; Mercorelli, B.; Alvisi, G.; Banks, L.; Palu, G.; Loregian, A.
Discovery of highly potent and selective influenza virus neuraminidase inhibitors targeting 150-cavity
2021 Jia, R.; Zhang, J.; Bertagnin, C.; Cherukupalli, S.; Ai, W.; Ding, X.; Li, Z.; Zhang, J.; Ju, H.; Ma, X.; Loregian, A.; Huang, B.; Zhan, P.; Liu, X.
Divide et impera: An In Silico Screening Targeting HCMV ppUL44 Processivity Factor Homodimerization Identifies Small Molecules Inhibiting Viral Replication
2021 Ghassabian, Hanieh; Falchi, F; Timmoneri, M; Mercorelli, B; Loregian, A; Palu, G; Alvisi, G
Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo'
2020 Lavezzo, Enrico; Franchin, Elisa; Ciavarella, Constanze; Cuomo-Dannenburg, Gina; Barzon, Luisa; Del Vecchio, Claudia; Rossi, Lucia; Manganelli, Riccardo; Loregian, Arianna; Navarin, Nicolò; Abate, Davide; Sciro, Manuela; Merigliano, Stefano; De Canale, Ettore; Vanuzzo, Maria Cristina; Besutti, Valeria; Saluzzo, Francesca; Onelia, Francesco; Pacenti, Monia; Parisi, Saverio; Carretta, Giovanni; Donato, Daniele; Flor, Luciano; Cocchio, Silvia; Masi, Giulia; Sperduti, Alessandro; Cattarino, Lorenzo; Salvador, Renato; Nicoletti, Michele; Caldart, Federico; Castelli, Gioele; Nieddu, Eleonora; Labella, Beatrice; Fava, Ludovico; Drigo, Matteo; Gaythorpe, Katy A M; Brazzale, Alessandra R; Toppo, Stefano; Trevisan, Marta; Baldo, Vincenzo; Donnelly, Christl A; Ferguson, Neil M; Dorigatti, Ilaria; Crisanti, Andrea
The Clinically Approved Antifungal Drug Posaconazole Inhibits Human Cytomegalovirus Replication
2020 Mercorelli, Beatrice; Luganini, Anna; Celegato, Marta; Palu', Giorgio; Gribaudo, Giorgio; Lepesheva, Galina I.; Loregian, Arianna
A novel small-molecule inhibitor of the human papillomavirus E6-p53 interaction that reactivates p53 function and blocks cancer cells growth
2020 Celegato, M.; Messa, L.; Goracci, L.; Mercorelli, B.; Bertagnin, C.; Spyrakis, F.; Suarez, I.; Cousido-Siah, A.; Trave, G.; Banks, L.; Cruciani, G.; Palu, G.; Loregian, A.
The isoquinoline alkaloid berberine inhibits human cytomegalovirus replication by interfering with the viral Immediate Early-2 (IE2) protein transactivating activity
2019 Luganini, Anna; Mercorelli, Beatrice; Messa, Lorenzo; Palù, Giorgio; Gribaudo, Giorgio; Loregian, Arianna
Potent and broad-spectrum cycloheptathiophene-3-carboxamide compounds that target the PA-PB1 interaction of influenza virus RNA polymerase and possess a high barrier to drug resistance
2019 Nannetti, Giulio; Massari, Serena; Mercorelli, Beatrice; Bertagnin, Chiara; Desantis, Jenny; Palù, Giorgio; Tabarrini, Oriana; Loregian, Arianna
Drug Repurposing Campaigns for Human Cytomegalovirus Identify a Natural Compound Targeting the Immediate-Early 2 (IE2) Protein: A Comment on "The Natural Flavonoid Compound Deguelin Inhibits HCMV Lytic Replication within Fibroblasts"
2019 Mercorelli, Beatrice; Luganini, Anna; Palù, Giorgio; Gribaudo, Giorgio; Loregian, Arianna
HPV16 E6 and E7 upregulate the histone lysine demethylase KDM2B through the c-MYC/miR-146a-5p axys
2018 Peta, Elektra; Sinigaglia, Alessandro; Masi, Giulia; Di Camillo, Barbara; Grassi, Angela; Trevisan, Marta; Messa, Lorenzo; Loregian, Arianna; Manfrin, Erminia; Brunelli, Matteo; Martignoni, Guido; Palù, Giorgio; Barzon, Luisa
Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction
2018 D'Agostino, Ilaria; Giacchello, Ilaria; Nannetti, Giulio; Fallacara, Anna Lucia; Deodato, Davide; Musumeci, Francesca; Grossi, Giancarlo; Palù, Giorgio; Cau, Ylenia; Trist, Iuni Margaret; Loregian, Arianna; Schenone, Silvia; Botta, Maurizio
A quantitative LumiFluo assay to test inhibitory compounds blocking p53 degradation induced by human papillomavirus oncoprotein E6 in living cells
2018 Messa, Lorenzo; Celegato, Marta; Bertagnin, Chiara; Mercorelli, Beatrice; Nannetti, Giulio; Palù, Giorgio; Loregian, Arianna
Structure-Based Optimization of N-Substituted Oseltamivir Derivatives as Potent Anti-Influenza A Virus Agents with Significantly Improved Potency against Oseltamivir-Resistant N1-H274Y Variant
2018 Zhang, Jian; Murugan, Natarajan Arul; Tian, Ye; Bertagnin, Chiara; Fang, Zengjun; Kang, Dongwei; Kong, Xiujie; Jia, Haiyong; Sun, Zhuosen; Jia, Ruifang; Gao, Ping; Poongavanam, Vasanthanathan; Loregian, Arianna; Xu, Wenfang; Ma, Xiuli; Ding, Xiao; Huang, Bing; Zhan, Peng; Liu, Xinyong
Drug Repurposing for Viral Infectious Diseases: How Far Are We?
2018 Mercorelli, Beatrice; Palù, Giorgio; Loregian, Arianna
A sensitive and validated HPLC-UV method for the quantitative determination of the new antifungal drug isavuconazole in human plasma
2018 Nannetti, Giulio; Pagni, Silvana; Palù, Giorgio; Loregian, Arianna
Repurposing the clinically approved calcium antagonist manidipine dihydrochloride as a new early inhibitor of human cytomegalovirus targeting the Immediate-Early 2 (IE2) protein
2018 Mercorelli, Beatrice; Luganini, Anna; Celegato, Marta; Palù, Giorgio; Gribaudo, Giorgio; Loregian, Arianna
Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant Variant
2018 Zhang, Jian; Poongavanam, Vasanthanathan; Kang, Dongwei; Bertagnin, Chiara; Lu, Huamei; Kong, Xiujie; Ju, Han; Lu, Xueyi; Gao, Ping; Tian, Ye; Jia, Haiyong; Desta, Samuel; Ding, Xiao; Sun, Lin; Fang, Zengjun; Huang, Boshi; Liang, Xuewu; Jia, Ruifang; Ma, Xiuli; Xu, Wenfang; Murugan, Natarajan Arul; Loregian, Arianna; Huang, Bing; Zhan, Peng; Liu, Xinyong
Corrigendum to “Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity” [Eur. J. Med. Chem. 138 (2017) 128–139] (S0223523417304610) (10.1016/j.ejmech.2017.06.015))
2018 Desantis, Jenny; Nannetti, Giulio; Massari, Serena; Barreca, Maria Letizia; Manfroni, Giuseppe; Cecchetti, Violetta; Palù, Giorgio; Goracci, Laura; Loregian, Arianna; Tabarrini, Oriana
Development and validation of a simple and robust HPLC method with UV detection for quantification of the hepatitis C virus inhibitor daclatasvir in human plasma
2017 Nannetti, Giulio; Messa, Lorenzo; Celegato, Marta; Pagni, Silvana; Basso, Monica; Parisi, Saverio G.; Palu', Giorgio; Loregian, Arianna
Efficient and regioselective one-step synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a] pyrimidine derivatives
2017 Massari, Serena; Desantis, Jenny; Nannetti, Giulio; Sabatini, Stefano; Tortorella, Sara; Goracci, Laura; Cecchetti, Violetta; Loregian, Arianna; Tabarrini, Oriana
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