NADAI, MATTEO
NADAI, MATTEO
The G-quadruplex experimental drug QN-302 impairs liposarcoma cell growth by inhibiting MDM2 expression and restoring p53 levels
2025 Tosoni, Beatrice; Naghshineh;, Eisa; Zanin, Irene; Gallina, Irene; Di Pietro;, Lorenzo; Cleris;, Loredana; Nadai, Matteo; Lecchi;, Mara; Verderio;, Paolo; Pratesi;, Pietro; Pasquali, Sandro; Zaffaroni;, Nadia; Neidle;, Stephen; Folini;, Marco; Richter, Sara
Naphthalene Diimide-Tetraazacycloalkane Conjugates Are G-Quadruplex-Based HIV-1 Inhibitors with a Dual Mode of Action
2024 Nadai, Matteo; Doria, Filippo; Frasson, Ilaria; Perrone, Rosalba; Pirota, Valentina; Bergamaschi, Greta; Freccero, Mauro; Richter, Sara N.
TERRA G-quadruplex stabilization as a new therapeutic strategy for multiple myeloma
2023 Scionti, Francesca; Juli, Giada; Rocca, Roberta; Polerà, Nicoletta; Nadai, Matteo; Grillone, Katia; Caracciolo, Daniele; Riillo, Caterina; Altomare, Emanuela; Ascrizzi, Serena; Caparello, Basilio; Cerra, Maria; Arbitrio, Mariamena; Richter, Sara N; Artese, Anna; Alcaro, Stefano; Tagliaferri, Pierosandro; Tassone, Pierfrancesco; Di Martino, Maria Teresa
Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties
2022 Rocca, Roberta; Scionti, Francesca; Nadai, Matteo; Moraca, Federica; Maruca, Annalisa; Costa, Giosuè; Catalano, Raffaella; Juli, Giada; Di Martino, Maria Teresa; Ortuso, Francesco; Alcaro, Stefano; Tagliaferri, Pierosandro; Tassone, Pierfrancesco; Richter, Sara N; Artese, Anna
Quindoline-derivatives display potent G-quadruplex-mediated antiviral activity against herpes simplex virus 1
2022 Frasson, Ilaria; Soldà, Paola; Nadai, Matteo; Tassinari, Martina; Scalabrin, Matteo; Gokhale, Vijay; Hurley, Laurence H; Richter, Sara N
Antiviral Activity of the G-Quadruplex Ligand TMPyP4 against Herpes Simplex Virus-1
2021 Artusi, Sara; Ruggiero, Emanuela; Nadai, Matteo; Tosoni, Beatrice; Perrone, Rosalba; Ferino, Annalisa; Zanin, Irene; Xodo, Luigi; Flamand, Louis; Richter, Sara N
Parallel G-quadruplexes recruit the HSV-1 transcription factor ICP4 to promote viral transcription in herpes virus-infected human cells
2021 Frasson, I.; Solda, P.; Nadai, M.; Lago, S.; Richter, S. N.
Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome
2021 Lago, Sara; Nadai, Matteo; Cernilogar, Filippo M; Kazerani, Maryam; Domíniguez Moreno, Helena; Schotta, Gunnar; Richter, Sara N
Selective Recognition of a Single HIV-1 G-Quadruplex by Ultrafast Small-Molecule Screening
2021 Scalabrin, M.; Nadai, M.; Tassinari, M.; Lago, S.; Doria, F.; Frasson, I.; Freccero, M.; Richter, S. N.
The MDM2 inducible promoter folds into four-tetrad antiparallel G-quadruplexes targetable to fight malignant liposarcoma
2021 Lago, S.; Nadai, M.; Ruggiero, E.; Tassinari, M.; Marusic, M.; Tosoni, B.; Frasson, I.; Cernilogar, F. M.; Pirota, V.; Doria, F.; Plavec, J.; Schotta, G.; Richter, S. N.
Novel monomolecular derivatives of the anti-HIV-1 G-quadruplex-forming Hotoda's aptamer containing inversion of polarity sites
2020 Virgilio, A.; Esposito, V.; Tassinari, M.; Nadai, M.; Richter, S. N.; Galeone, A.
Selective targeting of mutually exclusive DNA G-quadruplexes: HIV-1 LTR as paradigmatic model
2020 Tassinari, M.; Zuffo, M.; Nadai, M.; Pirota, V.; Sevilla Montalvo, A. C.; Doria, F.; Freccero, M.; Richter, S. N.
A dynamic i-motif with a duplex stem-loop in the long terminal repeat promoter of the HIV-1 proviral genome modulates viral transcription
2019 Ruggiero, Emanuela; Lago, Sara; Šket, Primož; Nadai, Matteo; Frasson, Ilaria; Plavec, Janez; Richter, Sara N
Conserved G-quadruplexes regulate the immediate early promoters of human alphaherpesviruses
2019 Frasson, I.; Nadai, M.; Richter, S. N.
Dyads of G-Quadruplex Ligands Triggering DNA Damage Response and Tumour Cell Growth Inhibition at Subnanomolar Concentration
2019 Doria, Federica; Salvati, E.; Pompili, L.; Pirota, V.; D'Angelo, C.; Manoli, F.; Nadai, M.; Richter, S. N.; Biroccio, A.; Manet, I.; Freccero, M.
G-Quadruplex Visualization in Cells via Antibody and Fluorescence Probe
2019 Nadai, Matteo; Richter, Sara N.
Naphthalene diimides as multimodal G-quadruplex-selective ligands
2019 Pirota, Valentina; Nadai, Matteo; Doria, Filippo; Richter, Sara N.
Stable and Conserved G-Quadruplexes in the Long Terminal Repeat Promoter of Retroviruses
2019 Ruggiero, Emanuela; Tassinari, Martina; Perrone, Rosalba; Nadai, Matteo; Richter, Sara N.
A Catalytic and Selective Scissoring Molecular Tool for Quadruplex Nucleic Acids
2018 Nadai, Matteo; Doria, Filippo; Scalabrin, Matteo; Pirota, Valentina; Grande, Vincenzo; Bergamaschi, Greta; Amendola, Valeria; Winnerdy, Fernaldo Richtia; Phan, Anh Tuân; Richter, Sara N.; Freccero, Mauro
A Fragment-Based Approach for the Development of G-Quadruplex Ligands: Role of the Amidoxime Moiety
2018 Tassinari, Martina; Lena, Alberto; Butovskaya, Elena; Pirota, Valentina; Nadai, Matteo; Freccero, Mauro; Doria, Filippo; Richter, Sara N