MEGGIO, FLAVIO
 Distribuzione geografica
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Continente #
NA - Nord America 10.515
AS - Asia 3.503
EU - Europa 2.071
AF - Africa 890
SA - Sud America 637
OC - Oceania 110
Continente sconosciuto - Info sul continente non disponibili 39
Totale 17.765
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Nazione #
US - Stati Uniti d'America 10.027
SG - Singapore 1.284
CN - Cina 655
HK - Hong Kong 429
BR - Brasile 327
DE - Germania 273
FI - Finlandia 265
VN - Vietnam 221
SE - Svezia 182
UA - Ucraina 144
FR - Francia 102
RU - Federazione Russa 101
PL - Polonia 96
IT - Italia 85
GB - Regno Unito 74
AR - Argentina 54
IN - India 44
NL - Olanda 44
AO - Angola 41
ID - Indonesia 41
IE - Irlanda 41
IQ - Iraq 41
AT - Austria 40
MX - Messico 40
EC - Ecuador 38
TT - Trinidad e Tobago 36
CV - Capo Verde 35
CZ - Repubblica Ceca 35
LV - Lettonia 34
NC - Nuova Caledonia 34
VE - Venezuela 34
PE - Perù 33
TR - Turchia 33
ES - Italia 32
JP - Giappone 32
NP - Nepal 32
PY - Paraguay 32
ZA - Sudafrica 32
JM - Giamaica 31
RO - Romania 31
CI - Costa d'Avorio 30
CO - Colombia 30
GE - Georgia 30
MA - Marocco 30
MN - Mongolia 30
SA - Arabia Saudita 30
TJ - Tagikistan 30
AZ - Azerbaigian 29
GT - Guatemala 29
DK - Danimarca 28
GA - Gabon 28
KR - Corea 28
MY - Malesia 28
SO - Somalia 28
ET - Etiopia 27
LA - Repubblica Popolare Democratica del Laos 27
TZ - Tanzania 27
AE - Emirati Arabi Uniti 26
BY - Bielorussia 26
BZ - Belize 26
CA - Canada 26
DZ - Algeria 26
GF - Guiana Francese 26
JO - Giordania 26
KG - Kirghizistan 26
MR - Mauritania 26
PT - Portogallo 26
TN - Tunisia 26
ZM - Zambia 26
AM - Armenia 25
BF - Burkina Faso 25
EE - Estonia 25
HU - Ungheria 25
IL - Israele 25
IS - Islanda 25
LC - Santa Lucia 25
PS - Palestinian Territory 25
SI - Slovenia 25
SK - Slovacchia (Repubblica Slovacca) 25
AL - Albania 24
BB - Barbados 24
HN - Honduras 24
LU - Lussemburgo 24
ME - Montenegro 24
NE - Niger 24
NI - Nicaragua 24
PK - Pakistan 24
UG - Uganda 24
BG - Bulgaria 23
DO - Repubblica Dominicana 23
NO - Norvegia 23
PH - Filippine 23
UZ - Uzbekistan 23
YE - Yemen 23
YT - Mayotte 23
BO - Bolivia 22
CL - Cile 22
GH - Ghana 22
IR - Iran 22
MG - Madagascar 22
Totale 16.723
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Città #
Fairfield 1.445
Woodbridge 1.119
Chandler 873
Ashburn 725
Singapore 701
Houston 685
Ann Arbor 608
Wilmington 602
Cambridge 541
Jacksonville 520
Seattle 509
Hong Kong 405
Boardman 244
Princeton 237
Beijing 179
San Diego 165
Santa Clara 126
Des Moines 122
Nanjing 99
Helsinki 93
Dong Ket 83
Medford 82
Bytom 65
Ho Chi Minh City 54
Chicago 41
Roxbury 41
Los Angeles 38
Hanoi 35
Luanda 35
Changsha 33
Noumea 33
Hebei 32
Nanchang 32
Vienna 32
Dublin 30
Dushanbe 30
Praia 30
Shenyang 30
Ulan Bator 30
Abidjan 28
Baku 28
Libreville 28
Munich 28
New York 28
Riga 28
Jiaxing 26
Lusaka 26
Addis Ababa 25
Amman 25
Norwalk 25
Guangzhou 24
Kampala 24
Nouakchott 24
Bridgetown 23
Castries 23
Managua 23
Niamey 23
Antananarivo 22
Kingston 22
Vientiane 22
Yerevan 22
Accra 21
Bishkek 21
Ouagadougou 21
Phnom Penh 20
Podgorica 20
São Paulo 20
Tashkent 20
Cayenne 19
Dallas 19
Dar es Salaam 19
Reykjavik 19
Tbilisi 19
Djibouti 18
Harare 18
Lima 18
Minsk 18
Salt Lake City 18
Tianjin 18
Dakar 17
Montevideo 17
Panama City 17
Tallinn 17
Conakry 16
Falls Church 16
Havana 16
Kharkiv 16
Kingstown 16
Ljubljana 16
Nairobi 16
Papeete 16
Willemstad 16
Buffalo 15
Guatemala City 15
La Paz 15
Lilongwe 15
Nassau 15
Redwood City 15
Athens 14
Chisinau 14
Totale 12.007
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Nome #
ATP Site-Directed Inhibitors of Protein Kinase CK2: An Update 268
Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA) 226
Inhibition of Protein Kinase CK2 by Flavonoids and Tyrphostins. A Structural Insight. 224
Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2 221
Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. 210
2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2 197
Basic residues in the 74-83 and 191-198 segments of protein kinase CK2 catalytic subunit are implicated in negative but not in positive regulation by the beta-subunit 187
Aurora-A site specificity: a study with synthetic peptide substrates 186
Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors 183
Inhibition of protein kinase CK2 by condensed polyphenolic derivatives. An in vitro and in vivo study 172
Development and exploitation of CK2 inhibitors 170
A noncanonical sequence phosphorylated by casein kinase 1 in beta-catenin may play a role in casein kinase 1 targeting of important signaling proteins 167
Structural features underlying the selectivity of the kinase inhibitors NBC and dNBC: role of a nitro group that discriminates between CK2 and DYRK1A 166
Plant Calreticulin is specifically and efficiently phosphorylated by protein kinase CK2. 164
Possible implication of the golgi apparatus casein kinase in the phosphorylation of vesicle docking protein p115 ser-940: a study with peptide substrates 164
The role of calcium in oligogalacturonide-activated signalling in soybean cells 162
Urolithin as a converging scaffold linking ellagic acid and coumarin analogues: design of potent protein kinase CK2 inhibitors. 162
Autophosphorylation at the regulatory beta subunit reflects the supramolecular organization of protein kinase CK2 160
The pleiotropic protein kinase CK2 phosphorylates HTLV-1 Tax protein in vitro, targeting its PDZ-binding motif 158
The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks 156
Synthetic peptides including acidic clusters as substrates of yeast casein kinase-2. 156
The selectivity of inhibitors of protein kinase CK2: an update 155
Understanding protein kinase CK2 mis-regulation upon F508del CFTR expression 155
Cystic fibrosis transmembrane regulator fragments with the Phe508 deletion exert a dual allosteric control over the master kinase CK2 153
Scouting Novel Protein Kinase A (PKA) Inhibitors by Using a Consensus Docking-Based Virtual Screening Approach 148
A study with model substrates of the structure of the sites phosphorylated by rat liver casein kinase TS. 148
Casein phosphatase dependent dephosphorylation of 32P-casein fractions labelled by two protein kinases. 148
Unique features of HIV-1 Rev protein phosphorylation by protein kinase CK2 ('casein kinase-2') 148
Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole 148
A Modified KESTREL Search Reveals a Basophilic Substrate Consensus for the Saccharomyces cerevisiae Npr1 Protein Kinase 146
Protein kinase CK2: a newcomer in the 'druggable kinome' 144
Phosphorylation of calmodulin fragments by protein kinase CK2. Mechanistic aspects and structural consequences 144
Toward the rational design of protein kinase casein kinase-2 inhibitors 143
Discrimination between the activity of protein kinase CK2 holoenzyme and its catalytic subunits 143
Spectroscopic studies of the mitochondrial targeting signal of the HTLV-1 P13II protein: a-helix formation and aggregation in lipophilic environments 141
Xenopus laevis occludin. Identification of in vitro phosphorylation sites by protein kinase CK2 and association with cingulin 141
Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization 140
Eukaryotic translation-initiation factor eIF2β binds to protein kinase CK2: Effects on CK2α activity 140
Dual role of calsequestrin as substrate and inhibitor of casein kinase-1 and casein kinase-2 139
Unprecedented Selectivity and Structural Determinants of a New Class of Protein Kinase CK2 Inhibitors in Clinical Trials for the Treatment of Cancer 139
Phosphorylation of casein fractions by rat liver 'phosvitin kinase'. 138
Phosphotyrosine specifies the phosphorylation by protein kinase CK2 of a peptide reproducing the activation loop of the insulin receptor protein tyrosine kinase. 134
Ca2+ binding protein calreticulin in Chlamydomonas reinhardtii (Chlorophyta): Biochemical characterization, differential expression during sexual reproduction and phylogenetic analysis. 132
POLYAMINES AS NEGATIVE REGULATORS OF CASEIN KINASE-2 - THE PHOSPHORYLATION OF CALMODULIN TRIGGERED BY POLYLYSINE AND BY THE ALPHA[66-86] PEPTIDE IS PREVENTED BY SPERMINE 130
Golgi apparatus mammary gland casein kinase: monitoring by a specific peptide substrate and definition of specificity determinants 129
Tetraiodobenzimidazoles are potent inhibitors of protein kinase CK2 129
Selectivity of 4,5,6,7-tetrabromo-benzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ("casein kinase-2") 129
Cystic fibrosis transmembrane regulator fragments with the Phe508 deletion exert a dual allosteric control over the master kinase CK2. 129
Linear motifs in the C-terminus of D. melanogaster cryptochrome 128
Cooperative modulation of protein kinase CK2 by separate domains of its regulatory beta-subunit 127
Modulation of protein kinase CK2 activity by fragments of CFTR encompassing F508 may reflect functional links with cystic fibrosis pathogenesis 126
Coumarin as attractive casein kinase 2(CK2) inhibitor scaffold: an integrated approach to elucidate the putative binding motif and explain structure-activity relationship. 126
The use of soybean trypsin inhibitors as phosphorylatable substrates for a rat liver protein kinase. 126
Design and synthesis of two new peptide substrates for the specific and sensitive monitoring of casein kinases-1 and -2. 125
Regulatory subunit of protein kinase CK2 contributes to the recognition of the substrate consensus sequence. A study with an eIF2 beta-derived peptide 124
The Dark Side of Protein Kinase CK2 Inhibition 123
Tyrosine versus serine/threonine phosphorylation by protein kinase casein kinase-2 - A study with peptide substrates derived from immunophilin Fpr3 122
Phosphorylation of alphaS2-casein by two rat liver 'casein kinases'. 122
Occludin dephosphorylation in early development of Xenopus laevis 121
Detection of type-2 casein kinase and its endogenous substrates in the components of the microsomal fraction of rat liver. 120
pCMB treatment reveals the essential role of cysteinyl residues in conferring functional competence to the regulatory subunit of protein kinase CK2 120
Different susceptibility of protein kinases to staurosporine inhibition. Kinetic studies and molecular bases for the resistance of protein kinase CK2 ('casein kinase-2) 120
Phosphorylation of HIV-1 Rev protein: implication of protein kinase CK2 and pro-directed kinases. 119
A new procedure for the measurement of the protein-kinase-catalyzed incorporation of the gamma-32P-phosphoryl group of ATP into phospho-proteins and phosphopeptides. 118
Different susceptibility of whole casein components to enzymatic phosphorylation by two forms of rat liver 'casein kinase'. 118
Identification of novel protein kinase CK1 delta (CK1 delta) inhibitors through structure-based virtual screening 116
Substrate recognition by casein kinase-II: The role of histidine-160 116
Phosphorylation of threonine and serine residues of native and partially dephosphorylated caseins by a rat liver cyclic AMP-insensitive protein kinase. 115
Casein kinases and their protein substrates in rat liver cytosol: evidence for their participation in multimolecular systems. 115
Functional conservation of Calreticulin in Euglena gracilis. 114
Physical dissection of the structural elements responsible for regulatory properties and intersubunit interactions of protein kinase CK2 beta-subunit 113
Site specificity of casein kinase-2 (TS) from rat liver cytosol. A study with model peptide substrates. 113
Calreticulin is expressed in Euglena gracilis 113
Biochemical evidence that the N terminal segment of the alpha-subunit and the ß-subunit play interchangeable roles in the activation of protein kinase CK2 112
Inhibition of rat liver cytosol casein kinases by heparin. 111
Synthetic peptides reproducing the site phosphorylated by cAMP-dependent protein kinase in protein phosphatase inhibitor-1. Effect of structural modifications on the phosphorylation efficiency. 111
The comparative efficiencies of the Ser(P)-, Thr(P)- and Tyr(P)-residues as specificity determinants for casein kinase-1. 111
Biochemical properties of native forms of DMPK. 110
Ribofuranosyl-benzimidazole derivatives as inhibitors of casein kinase-2 and casein kinase-1. 110
Phosphorylation and activation of protein kinase CK2 by p34cdc2 are independent events. 110
Polycation-dependent, Ca2+-antagonized phosphorylation of calmodulin by casein kinase-2 and a spleen tyrosine protein kinase. 110
Structural Features Underlying the Unusual Mode of Calmodulin Phosphorylation by Protein Kinase CK2: A Study with Synthetic Calmodulin Fragments 109
Rapid and reliable identification of "casein kinases TS" in many tissues by means of a new specific and very suitable model substrate. 108
Role of phosphorylated aminoacyl residues in generating atypical consensus sequences which are recognized by casein kinase-2 but not by casein kinase-1. 108
Cross talk between protein kinase CK2 and eukaryotic translation initiation factor eIF2beta subunit. 108
Inhibition of oligosaccharide-elicited Ca2+ transients by 4,5,6,7-tetrabromobenzotriazole in Arabidopsis cell cultures 107
Subunit structure and autophosphorylation mechanism of casein kinase-TS (type-2) from rat liver cytosol. 107
Rat liver casein kinases> substrate specificity and structural requirements 107
Dephosphorylation of synthetic phosphopeptides by protein phosphatase-T, a phosphothreonyl protein phosphatase. 106
Phosphorylation of troponin T by casein kinase TS. 106
Phosphotyrosine as a specificity determinant for casein kinase-2, a growth related Ser/Thr-specific protein kinase. 105
Phosphorylation activity of endogenous myotonic dystrophy protein kinase. 103
HIV-1 Rev transactivator: a beta-subunit directed substrate and effector of protein kinase CK2 103
Studies on the structural requirements of a microsomal cAMP-independent protein kinase. 103
Phosphorylation of src-phosphopeptides by casein kinases-1 and -2: favourable effect of phosphotyrosine. 103
Functional analysis of CK2beta-derived synthetic fragments 102
Structural features determining the site specificity of a rat liver cAMP-independent protein kinase. 102
Dissection of the dual function of the β-subunit of protein kinase CK2 (‘casein kinase-2’): a synthetic peptide reproducing the carboxyl-terminal domain mimicks the positive but not the negative effects of the whole protein 101
The carboxy-terminal domain of Grp94 binds to protein kinase CK2 alpha but not to CK2 holoenzyme 100
Partially dephosphorylated phosphopeptide AcSer(P)-Ser(P)-Ser(P) is an excellent substrate for casein kinase-2. 100
Totale 13.545
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Categoria #
all - tutte 56.207
article - articoli 51.852
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 244
selected - selezionate 0
volume - volumi 1.079
Totale 109.382
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.057 0 0 0 0 111 130 37 130 214 111 172 152
2021/20221.957 19 238 306 167 57 98 92 253 67 14 265 381
2022/20231.672 297 186 13 237 300 263 4 117 178 8 55 14
2023/2024553 25 108 54 28 70 49 30 26 12 12 88 51
2024/20252.438 4 196 128 120 393 64 81 186 186 75 441 564
2025/20264.728 267 891 1.495 1.685 390 0 0 0 0 0 0 0
Totale 17.786