SCCA-IgM as a Potential Biomarker of Non-Alcoholic Fatty Liver Disease in Patients with Obesity, Prediabetes and Diabetes Undergoing Sleeve Gastrectomy

Bettini, Silvia; Bordigato, Emanuel; Milan, Gabriella; Dal Pra', Chiara; Favaretto, Francesca; Belligoli, Anna; Sanna, Marta; Serra, Roberto; Foletto, Mirto; Prevedello, Luca; Busetto, Luca; Fassina, Giorgio; Vettor, Roberto; Fabris, Roberto

doi:10.1159/000499717

Non-alcoholic fatty liver disease (NAFLD) has a high prevalence in obesity and its presence should be screened. Laparoscopic sleeve gastrectomy (LSG) is an effective treatment for obesity, but its effects on NAFLD are still to be firmly established. The diagnosis of non-alcoholic steatohepatitis (NASH) is currently performed by liver biopsy, a costly and invasive procedure. Squamous cell carcinoma antigen-IgM (SCCA-IgM) is a biomarker of viral hepatitis to hepatocellular carcinoma development and its role in NAFLD to NASH progression has not yet been investigated.

Titolo:	SCCA-IgM as a Potential Biomarker of Non-Alcoholic Fatty Liver Disease in Patients with Obesity, Prediabetes and Diabetes Undergoing Sleeve Gastrectomy
Autori:	BETTINI, SILVIA BORDIGATO, EMANUEL MILAN, GABRIELLA DAL PRA, CHIARA FAVARETTO, FRANCESCA BELLIGOLI, ANNA SANNA, MARTA SERRA, ROBERTO FOLETTO, MIRTO PREVEDELLO, LUCA BUSETTO, LUCA Fassina, Giorgio VETTOR, ROBERTO FABRIS, ROBERTO mostra contributor esterni nascondi contributor esterni
Data di pubblicazione:	2019
Rivista:	OBESITY FACTS
Abstract:	Non-alcoholic fatty liver disease (NAFLD) has a high prevalence in obesity and its presence should be screened. Laparoscopic sleeve gastrectomy (LSG) is an effective treatment for obesity, but its effects on NAFLD are still to be firmly established. The diagnosis of non-alcoholic steatohepatitis (NASH) is currently performed by liver biopsy, a costly and invasive procedure. Squamous cell carcinoma antigen-IgM (SCCA-IgM) is a biomarker of viral hepatitis to hepatocellular carcinoma development and its role in NAFLD to NASH progression has not yet been investigated.
Handle:	http://hdl.handle.net/11577/3303217
Appare nelle tipologie:	01.01 - Articolo in rivista

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