Sfoglia per Autore
NADH Shuttling Couples Cytosolic Reductive Carboxylation of Glutamine with Glycolysis in Cells with Mitochondrial Dysfunction
2018 Gaude, Edoardo; Schmidt, Christina; Gammage, Payam A; Dugourd, Aurelien; Blacker, Thomas; Chew, Sew Peak; Saez-Rodriguez, Julio; O'Neill, John S; Szabadkai, Gyorgy; Minczuk, Michal; Frezza, Christian
Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases
2018 Giorgi, Carlotta; Marchi, Saverio; Simoes, Ines C. M.; Ren, Ziyu; Morciano, Giampaolo; Perrone, Mariasole; Patalas-Krawczyk, Paulina; Borchard, Sabine; Jędrak, Paulina; Pierzynowska, Karolina; Szymański, Jędrzej; Wang, David Q.; Portincasa, Piero; Węgrzyn, Grzegorz; Zischka, Hans; Dobrzyn, Pawel; Bonora, Massimo; Duszynski, Jerzy; Rimessi, Alessandro; Karkucinska-Wieckowska, Agnieszka; Dobrzyn, Agnieszka; Szabadkai, Gyorgy; Zavan, Barbara; Oliveira, Paulo J.; Sardao, Vilma A.; Pinton, Paolo; Wieckowski, Mariusz R.
Targeting RORs nuclear receptors by novel synthetic steroidal inverse agonists for autoimmune disorders
2018 DAL PRA', Matteo; Carta, Davide; Szabadkai, Gyorgy; Suman, Matteo; Frión-Herrera, Yahima; Paccagnella, Nicola; Castellani, Giulia; De Martin, Sara; Ferlin, Maria Grazia
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
2018 Galluzzi, Lorenzo; Vitale, Ilio; Aaronson, S. A.; Abrams, J. M.; Adam, Dieter; Agostinis, Patrizia; Alnemri, E. S.; Altucci, Lucia; Amelio, Ivano; Andrews, D. W.; Annicchiarico-Petruzzelli, Margherita; Antonov, A. V.; Arama, Eli; Baehrecke, E. H.; Barlev, N. A.; Bazan, N. G.; Bernassola, Francesca; Bertrand, M. J. M.; Bianchi, Katiuscia; Blagosklonny, M. V.; Blomgren, Klas; Borner, Christoph; Boya, Patricia; Brenner, Catherine; Campanella, Michelangelo; Candi, Eleonora; Carmona-Gutierrez, Didac; Cecconi, Francesco; Chan, F. K. -M.; Chandel, N. S.; Cheng, E. H.; Chipuk, J. E.; Cidlowski, J. A.; Ciechanover, Aaron; Cohen, G. M.; Conrad, Marcus; Cubillos-Ruiz, J. R.; Czabotar, P. E.; D'Angiolella, Vincenzo; Dawson, T. M.; Dawson, V. L.; de Laurenzi, Vincenzo; de Maria, Ruggero; Debatin, Klaus-Michael; Deberardinis, R. J.; Deshmukh, Mohanish; Di Daniele, Nicola; Di Virgilio, Francesco; Dixit, V. M.; Dixon, S. J.; Duckett, C. S.; Dynlacht, B. D.; El-Deiry, W. S.; Elrod, J. W.; Fimia, Gian Maria; Fulda, Simone; García-Sáez, A. J.; Garg, A. D.; GARRIDO PEREZ, MARIA DEL CARMEN; Gavathiotis, Evripidis; Golstein, Pierre; Gottlieb, Eyal; Green, D. R.; Greene, L. A.; Gronemeyer, Hinrich; Gross, Atan; Hajnoczky, Gyorgy; Hardwick, J. M.; Harris, I. S.; Hengartner, M. O.; Hetz, Claudio; Ichijo, Hidenori; Jäättelä, Marja; Joseph, Bertrand; Jost, P. J.; Juin, P. P.; Kaiser, W. J.; Karin, Michael; Kaufmann, Thomas; Kepp, Oliver; Kimchi, Adi; Kitsis, R. N.; Klionsky, D. J.; Knight, R. A.; Kumar, Sharad; Lee, S. W.; Lemasters, J. J.; Levine, Beth; Linkermann, Andreas; Lipton, S. A.; Lockshin, R. A.; López-Otín, Carlos; Lowe, S. W.; Luedde, Tom; Lugli, Enrico; Macfarlane, Marion; Madeo, Frank; Malewicz, Michal; Malorni, Walter; Manic, Gwenola; Marine, Jean-Christophe; Martin, S. J.; Martinou, Jean-Claude; Medema, Jan Paul; Mehlen, Patrick; Meier, Pascal; Melino, Sonia; Miao, E. A.; Molkentin, J. D.; Moll, U. M.; Muñoz-Pinedo, Cristina; Nagata, Shigekazu; Nuñez, Gabriel; Oberst, Andrew; Oren, Moshe; Overholtzer, Michael; Pagano, Michele; Panaretakis, Theocharis; Pasparakis, Manolis; Penninger, J. M.; Pereira, D. M.; Pervaiz, Shazib; Peter, M. E.; Piacentini, Mauro; Pinton, Paolo; Prehn, J. H. M.; Puthalakath, Hamsa; Rabinovich, G. A.; Rehm, Markus; Rizzuto, Rosario; Rodrigues, C. M. P.; Rubinsztein, DAVID CHAIM; Rudel, Thomas; Ryan, K. M.; Sayan, Emre; Scorrano, Luca; Shao, Feng; Shi, Yufang; Silke, John; Simon, Hans-Uwe; Sistigu, Antonella; Stockwell, B. R.; Strasser, Andreas; Szabadkai, Gyorgy; Tait, S. W. G.; Tang, Daolin; Tavernarakis, Nektarios; Thorburn, Andrew; Tsujimoto, Yoshihide; Turk, Boris; Vanden Berghe, Tom; Vandenabeele, Peter; Vander Heiden, M. G.; Villunger, Andreas; Virgin, H. W.; Vousden, K. H.; Vucic, Domagoj; Wagner, E. F.; Walczak, Henning; Wallach, David; Wang, Ying; Wells, J. A.; Wood, Will; Yuan, Junying; Zakeri, Zahra; Zhivotovsky, Boris; Zitvogel, Laurence; Melino, Gerry; Kroemer, Guido
Protein CoAlation: A Redox-Regulated Protein Modification by Coenzyme Ain Mammalian Cells
2017 Tsuchiya, Yugo; Peak Chew, Sew; Newell, Clare; Miller Aidoo, Sheritta; Mangal, Sriyash; Zhyvoloup, Alexander; Baković, Jovana; Malanchuk, Oksana; Pereira, Gonçalo; Kotiadis, Vassilios; Szabadkai, Gyorgy; Duchen, Michael; Campbell, Mark; Rodriguez Cuenca, Sergio; Vidal Puig, Antonio; Mcneil, JAMES ANDREW; Murphy, Michael P; Filonenko, Valeriy; Skehel, Mark; Gout, Ivan
MCbiclust: A novel algorithm to discover large-scale functionally related gene sets from massive transcriptomics data collections
2017 Bentham, ROBERT BENJAMIN; Bryson, Kevin; Szabadkai, Gyorgy
Mitochondrial permeability transition pore: Sensitivity to opening and mechanistic dependence on substrate availability
2017 Briston, Thomas; Roberts, Malcolm; Lewis, Sian; Powney, Ben; Staddon, James M.; Szabadkai, Gyorgy; Duchen, Michael R.
Assessment of Cellular Redox State Using NAD(P)H Fluorescence Intensity and Lifetime
2017 Blacker, Thomas S; Berecz, Tunde; Duchen, Michael R; Szabadkai, Gyorgy
Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism
2017 Bilanges, Benoit; Alliouachene, Samira; Pearce, Wayne; Morelli, Daniele; Szabadkai, Gyorgy; Chung, Yuen-Li; Chicanne, Gaëtan; Valet, Colin; Hill, Julia M.; Voshol, Peter J.; Collinson, Lucy; Peddie, Christopher; Ali, Khaled; Ghazaly, Essam; Rajeeve, Vinothini; Trichas, Georgios; Srinivas, Shankar; Chaussade, Claire; Salamon, Rachel S.; Backer, Jonathan M.; Scudamore, Cheryl L.; Whitehead, Maria A.; Keaney, Erin P.; Murphy, Leon O.; Semple, Robert K.; Payrastre, Bernard; Tooze, Sharon A.; Vanhaesebroeck, Bart
mTORC1-independent autophagy regulates receptor tyrosine kinase phosphorylation in colorectal cancer cells via an mTORC2-mediated mechanism
2017 Lampada, Aikaterini; O'Prey, James; Szabadkai, Gyorgy; Ryan, Kevin M; Hochhauser, Daniel; Salomoni, Paolo
Pathological consequences of MICU1 mutations on mitochondrial calcium signalling and bioenergetics
2017 Bhosale, Gauri; Sharpe, Jenny A.; Koh, Amanda; Kouli, Antonina; Szabadkai, Gyorgy; Duchen, Michael R.
Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria
2016 Briston, Thomas; Lewis, Sian; Koglin, Mumta; Mistry, Kavita; Shen, Yongchun; Hartopp, Naomi; Katsumata, Ryosuke; Fukumoto, Hironori; Duchen, Michael R.; Szabadkai, Gyorgy; Staddon, James M.; Roberts, Malcolm; Powney, Ben
Selective inhibition of the mitochondrial permeability transition pore protects against neurodegeneration in experimental multiple sclerosis
2016 Warne, Justin; Pryce, Gareth; Hill, Julia M.; Shi, Xiao; Lennerås, Felicia; Puentes, Fabiola; Kip, Maarten; Hilditch, Laura; Walker, Paul; Simone, Michela I.; Chan, A. W. Edith; Towers, Greg J.; Coker, Alun R.; Duchen, Michael R.; Szabadkai, Gyorgy; Baker, David; Selwood, David L.
The mitochondrial calcium uniporter regulates breast cancer progression via HIF-1α
2016 Tosatto, Anna; Sommaggio, Roberta; Kummerow, Carsten; Bentham, Robert B; Blacker, Thomas S; Berecz, Tunde; Duchen, Michael R; Rosato, Antonio; Bogeski, Ivan; Szabadkai, Gyorgy; Rizzuto, Rosario; Mammucari, Cristina
The regulation of neuronal mitochondrial metabolism by calcium
2015 Llorente Folch, I.; Rueda, C. B.; Pardo, B.; Szabadkai, Gyorgy; Duchen, M. R.; Satrustegui, J.
Essential versus accessory aspects of cell death: Recommendations of the NCCD 2015
2015 Galluzzi, Lorenzo; Bravo San Pedro, J. M.; Vitale, IGOR VASLAV; Aaronson, S. A.; Abrams, J. M.; Adam, MADALINA DANIELA; Alnemri, E. S.; Altucci, L.; Andrews, D.; Annicchiarico Petruzzelli, M.; Baehrecke, E. H.; Bazan, N. G.; Bertrand, M. J.; Bianchi, Katiuscia; Blagosklonny, M. V.; Blomgren, K.; Borner, C.; Bredesen, D. E.; Brenner, C.; Campanella, M.; Candi, E.; Cecconi, F.; Chan, F. K.; Chandel, NAVDEEP SINGH; Cheng, E. H.; Chipuk, J. E.; Cidlowski, J. A.; Ciechanover, A.; Dawson, T. M.; Dawson, V. L.; De Laurenzi, V.; De Maria, R.; Debatin, K. M.; Di Daniele, N.; Dixit, V. M.; Dynlacht, B. D.; El Deiry, W. S.; Fimia, G. M.; Flavell, R. A.; Fulda, S.; Garrido, C.; Gougeon, M. L.; Green, D. R.; Gronemeyer, H.; Hajnoczky, Gyorgy; Hardwick, J. M.; Hengartner, M. O.; Ichijo, H.; Joseph, B.; Jost, P. J.; Kaufmann, T.; Kepp, O.; Klionsky, D. J.; Knight, R. A.; Kumar, S.; Lemasters, J. J.; Levine, B.; Linkermann, A.; Lipton, S. A.; Lockshin, R. A.; López Otín, C.; Lugli, E.; Madeo, FRANK PAUL FRANCESCO; Malorni, W.; Marine, J. C.; Martin, S. J.; Martinou, J. C.; Medema, J. P.; Meier, P.; Melino, S.; Mizushima, N.; Moll, U.; Muñoz Pinedo, C.; Nuñez, G.; Oberst, A.; Panaretakis, T.; Penninger, J. M.; Peter, M. E.; Piacentini, M.; Pinton, Paolo; Prehn, J. H.; Puthalakath, H.; Rabinovich, G. A.; Ravichandran, K. S.; Rizzuto, Rosario; Rodrigues, C. M.; Rubinsztein, D. C.; Rudel, T.; Shi, Y.; Simon, H. U.; Stockwell, B. R.; Szabadkai, Gyorgy; Tait, S. W.; Tang, H. L.; Tavernarakis, N.; Tsujimoto, Y.; Vanden Berghe, T.; Vandenabeele, P.; Villunger, A.; Wagner, E. F.; Walczak, H.; White, E.; Wood, W. G.; Yuan, J.; Zakeri, Z.; Zhivotovsky, Boris; Melino, G.; Kroemer, G.
Genetic defects in mitochondrial calcium handling cause neuromuscular disease
2014 Logan, C. V.; Sharpe, J. A.; DE STEFANI, Diego; Raffaello, Anna; Rizzuto, Rosario; Duchen, M. R.; Muntoni, F; Sheridan, E; Szabadkai, Gyorgy
Separating NADH and NADPH fluorescence in live cells and tissues using FLIM.
2014 Blacker, Ts; Mann, Zf; Gale, Je; Ziegler, M; Bain, Aj; Szabadkai, Gyorgy; Duchen, Mr
Measuring baseline Ca2+ levels in subcellular compartments using genetically engineered fluorescent indicators
2014 Hill, Julia M.; DE STEFANI, Diego; Jones, Aleck W. E.; Ruiz, Asier; Rizzuto, Rosario; Szabadkai, Gyorgy
Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling.
2014 Logan, Cv; Szabadkai, Gyorgy; Sharpe, Ja; Parry, Da; Torelli, S; Childs, Am; Kriek, M; Phadke, R; Johnson, Ca; Roberts, Ny; Bonthron, Dt; Pysden, Ka; Whyte, T; Munteanu, I; Foley, Ar; Wheway, G; Szymanska, K; Natarajan, S; Abdelhamed, Za; Morgan, Je; Roper, H; Santen, Gw; Niks, Eh; van der Pol, Wl; Lindhout, D; Raffaello, Anna; DE STEFANI, Diego; den Dunnen, Jt; Sun, Y; Ginjaar, I; Sewry, Ca; Hurles, M; Rizzuto, Rosario; Duchen, Mr; Muntoni, F; Sheridan, E; Uk10k, Consortium
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