Sfoglia per Autore
LRRK2 signaling in neurodegeneration: two decades of progress
2021 Iannotta, Lucia; Greggio, Elisa
LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation
2021 Pischedda, F.; Cirnaru, M. D.; Ponzoni, L.; Sandre, M.; Biosa, A.; Carrion, M. P.; Marin, O.; Morari, M.; Pan, L.; Greggio, E.; Bandopadhyay, R.; Sala, M.; Piccoli, G.
Pathways to Parkinson's disease: a spotlight on 14-3-3 proteins
2021 Giusto, E; Yacoubian, T A; Greggio, E; Civiero, L
Leucine-rich repeat kinase 2 (LRRK2) and Parkinson’s disease: From genetics to pathobiology
2020 Cogo, S.; Greggio, E.
Extracellular clusterin limits the uptake of α-synuclein fibrils by murine and human astrocytes
2020 Filippini, Alice; Mutti, Veronica; Faustini, Gaia; Longhena, Francesca; Ramazzina, Ileana; Rizzi, Federica; Kaganovich, Alice; Roosen, Dorien A; Landeck, Natalie; Duffy, Megan; Tessari, Isabella; Bono, Federica; Fiorentini, Chiara; Greggio, Elisa; Bubacco, Luigi; Bellucci, Arianna; Missale, Mariacristina; Cookson, Mark R; Gennarelli, Massimo; Russo, Isabella
Divergent Effects of G2019S and R1441C LRRK2 Mutations on LRRK2 and Rab10 Phosphorylations in Mouse Tissues
2020 Iannotta, Lucia; Biosa, Alice; Kluss, Jillian H; Tombesi, Giulia; Kaganovich, Alice; Cogo, Susanna; Plotegher, Nicoletta; Civiero, Laura; Lobbestael, Evy; Baekelandt, Veerle; Cookson, Mark R; Greggio, Elisa
Co-occurring WARS2 and CHRNA6 mutations in a child with a severe form of infantile parkinsonism
2020 Martinelli, S.; Cordeddu, V.; Galosi, S.; Lanzo, A.; Palma, E.; Pannone, L.; Ciolfi, A.; Di Nottia, M.; Rizza, T.; Bocchinfuso, G.; Traversa, A.; Caputo, V.; Farrotti, A.; Carducci, C.; Bernardini, L.; Cogo, S.; Paglione, M.; Venditti, M.; Bentivoglio, A.; Ng, J.; Kurian, M. A.; Civiero, L.; Greggio, E.; Stella, L.; Trettel, F.; Sciaccaluga, M.; Roseti, C.; Carrozzo, R.; Fucile, S.; Limatola, C.; Di Schiavi, E.; Tartaglia, M.; Leuzzi, V.
Leucine-rich repeat kinase 2 and lysosomal dyshomeostasis in Parkinson disease
2019 Cogo, S.; Manzoni, C.; Lewis, P. A.; Greggio, E.
Levetiracetam treatment ameliorates LRRK2 pathological mutant phenotype
2019 Rassu, M.; Biosa, A.; Galioto, M.; Fais, M.; Sini, P.; Greggio, E.; Piccoli, G.; Crosio, C.; Iaccarino, C.
Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils
2019 Russo, I.; Kaganovich, A.; Ding, J.; Landeck, N.; Mamais, A.; Varanita, T.; Biosa, A.; Tessari, I.; Bubacco, L.; Greggio, E.; Cookson, M. R.
The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A
2019 Rivero-Rios, P.; Romo-Lozano, M.; Madero-Perez, J.; Thomas, A. P.; Biosa, A.; Greggio, E.; Hilfiker, S.
Leucine-rich repeat kinase 2 phosphorylation on synapsin I regulates glutamate release at pre-synaptic sites
2019 Marte, A.; Russo, I.; Rebosio, C.; Valente, P.; Belluzzi, E.; Pischedda, F.; Montani, C.; Lavarello, C.; Petretto, A.; Fedele, E.; Baldelli, P.; Benfenati, F.; Piccoli, G.; Greggio, E.; Onofri, F.
Ceramides in Parkinson's Disease: From Recent Evidence to New Hypotheses
2019 Plotegher, Nicoletta; Bubacco, Luigi; Greggio, Elisa; Civiero, Laura
Kinase activity of mutant LRRK2 manifests differently in hetero-dimeric vs. Homo-dimeric complexes
2019 Leandrou, E.; Markidi, E.; Memou, A.; Melachroinou, K.; Greggio, E.; Rideout, H. J.
Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation
2018 Madero-Pérez, J.; Fdez, E.; Fernández, B.; Lara Ordóñez, A. J.; Blanca Ramírez, M.; Gómez-Suaga, P.; Waschbüsch, D.; Lobbestael, E.; Baekelandt, V.; Nairn, A. C.; Ruiz-Martínez, J.; Aiastui, A.; López De Munain, A.; Lis, P.; Comptdaer, T.; Taymans, J. M.; Chartier-Harlin, M. C.; Beilina, A.; Gonnelli, A.; Cookson, M. R.; Greggio, E.; Hilfiker, S.
The role of LRRK2 in cytoskeletal dynamics
2018 Civiero, Laura; Cogo, Susanna; Biosa, Alice; Greggio, Elisa
Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation
2018 Madero-Pérez, Jesús; Fdez, Elena; Fernández, Belén; Lara Ordóñez, Antonio J.; Blanca Ramírez, Marian; Gómez-Suaga, Patricia; Waschbüsch, Dieter; Lobbestael, Evy; Baekelandt, Veerle; Nairn, Angus C.; Ruiz-Martínez, Javier; Aiastui, Ana; López De Munain, Adolfo; Lis, Pawel; Comptdaer, Thomas; Taymans, Jean-Marc; Chartier-Harlin, Marie-Christine; Beilina, Alexandria; Gonnelli, Adriano; Cookson, Mark R.; Greggio, Elisa; Hilfiker, Sabine
The LRRK2 variant E193K prevents mitochondrial fission upon MPP+ treatment by altering LRRK2 binding to DRP1
2018 Perez Carrion, Maria; Pischedda, Francesca; Biosa, Alice; Russo, Isabella; Straniero, Letizia; Civiero, Laura; Guida, Marianna; Gloeckner, Christian J.; Ticozzi, Nicola; Tiloca, Cinzia; Mariani, Claudio; Pezzoli, Gianni; Duga, Stefano; Pichler, Irene; Pan, Lifeng; Landers, John E.; Greggio, Elisa; Hess, Michael W.; Goldwurm, Stefano; Piccoli, Giovanni
Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4
2018 Russo, Isabella; Di Benedetto, Giulietta; Kaganovich, Alice; Ding, Jinhui; Mercatelli, Daniela; Morari, Michele; Cookson, Mark R.; Bubacco, Luigi; Greggio, Elisa
Molecular insights and functional implication of LRRK2 dimerization
2017 Civiero, Laura; Russo, Isabella; Bubacco, Luigi; Greggio, Elisa
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