PIRAZZINI, MARCO
PIRAZZINI, MARCO
Dipartimento di Scienze Biomediche - DSB
Re-Assembled Botulinum Neurotoxin inhibits CNS functions without systemic toxicity
2011 Ferrari, E; Maywood, Es; Restani, L; Caleo, M; Pirazzini, M; Rossetto, O; Hastings, Mh; Niranjan, D; Schiavo, G; Davletov, B
pH-sensitive PEG-based micelles for tumor targeting
2011 Salmaso, Stefano; Bersani, Sara; Pirazzini, Marco; Caliceti, Paolo
Re-Assembled Botulinum Neurotoxin Inhibits CNS Functions without Systemic Toxicity
2011 Ferrari, E; Maywood, Es; Restani, L; Caleo, M; Pirazzini, Marco; Rossetto, Ornella; Hastings, Mh; Niranjan, D; Schiavo, G; Davletov, B.
Double anchorage to the membrane and intact inter-chain disulfide bond are required for the low pH induced entry of tetanus and botulinum neurotoxins into neurons
2011 Pirazzini, Marco; Rossetto, Ornella; Bolognese, Paolo; Shone, Cc; Montecucco, Cesare
An update on the mechanism of action of tetanus and botulinum neurotoxins.
2011 Rossetto, Ornella; Pirazzini, Marco; Bolognese, P.; Rigoni, Michela; Montecucco, Cesare
Botulinum Neurotoxin Type A is Internalized and Translocated from Small Synaptic Vesicles at the Neuromuscular Junction.
2013 Colasante, C; Rossetto, Ornella; Morbiato, L; Pirazzini, Marco; Molgó, J; Montecucco, Cesare
The thioredoxin reductase-thioredoxin system is involved in the entry of tetanus and botulinum neurotoxins in the cytosol of nerve terminals
2013 Pirazzini, Marco; Bordin, Fulvio; Rossetto, Ornella; Clifford C., Shone; Thomas, Binz; Montecucco, Cesare
Botulinum neurotoxin serotype D is poorly effective in humans: an in vivo electrophysiological study
2013 Roberto, Eleopra; Montecucco, Cesare; Grazia, Devigili; Md, ; Christian, Lettieri; Sara, Rinaldo; Lorenzo, Verriello; Pirazzini, Marco; Caccin, Paola; Rossetto, Ornella
Time course and temperature dependence of the membrane translocation of tetanus and botulinum neurotoxins C and D in neurons
2013 Pirazzini, Marco; Rossetto, Ornella; Cristina, Bertasio; Bordin, Fulvio; Clifford C., Shone; Thomas, Binz; Montecucco, Cesare
Neutralisation of specific surface carboxylates speeds up translocation of botulinum neurotoxin type B enzymatic domain
2013 Pirazzini, Marco; Tina, Henke; Rossetto, Ornella; Stefan, Mahrhold; Nadja, Krez; Andreas, Rummel; Montecucco, Cesare; Thomas, Binz
The entry of tetanus and botulinum neurotoxins into neurons
2013 Pirazzini, Marco
Thioredoxin and Its Reductase Are Present on Synaptic Vesicles, and Their Inhibition Prevents the Paralysis Induced by Botulinum Neurotoxins
2014 Pirazzini, Marco; Domenico, Azarnia?tehran; Giulia, Zanetti; Megighian, Aram; Michele, Scorzeto; Silvia, Fillo; Shone, C. l. i. f. f. o. r. d. ?. C.; Thomas, Binz; Rossetto, Ornella; Florigio, Lista; Montecucco, Cesare
Botulinum neurotoxins: genetic, structural and mechanistic insights
2014 Rossetto, Ornella; Pirazzini, Marco; Montecucco, Cesare
Thioredoxin and its reductase are present on synaptic vesicles, and their inhibition prevents the paralysis induced by botulinum neurotoxins
2014 Pirazzini, Marco; Tehran, Domenico Azarnia; Zanetti, Giulia; Megighian, Aram; Scorzeto, Michele; Fillo, Silvia; Shone, Clifford C.; Binz, Thomas; Rossetto, Ornella; Lista, Florigio; Montecucco, Cesare
Diphtheria Toxin conformational switching at acidic pH
2014 Leka, Oneda; Vallese, Francesca; Pirazzini, Marco; Berto, Paola; Montecucco, Cesare; Zanotti, Giuseppe
The thioredoxin reductase - Thioredoxin redox system cleaves the interchain disulphide bond of botulinum neurotoxins on the cytosolic surface of synaptic vesicles
2015 Pirazzini, Marco; Tehran, Domenico Azarnia; Zanetti, Giulia; Lista, Florigio; Binz, Thomas; Shone, Clifford C.; Rossetto, Ornella; Montecucco, Cesare
A novel inhibitor prevents the peripheral neuroparalysis of Botulinum neurotoxins
2015 AZARNIA TEHRAN, Domenico; Zanetti, Giulia; Leka, Oneda; Lista, Florigio; Fillo, Silvia; Binz, Thomas; Shone, Clifford C.; Rossetto, Ornella; Montecucco, Cesare; Paradisi, Cristina; Mattarei, Andrea; Pirazzini, Marco
Snake and spider toxins induce a rapid recovery of function of botulinum neurotoxin paralysed neuromuscular junction
2015 Duregotti, Elisa; Zanetti, Giulia; Scorzeto, M.; Megighian, Aram; Montecucco, Cesare; Pirazzini, Marco; Rigoni, Michela
Current gaps in basic science knowledge of botulinum neurotoxin biological actions
2015 Rossetto, Ornella; Pirazzini, Marco; Montecucco, Cesare
On the translocation of botulinum and tetanus neurotoxins across the membrane of acidic intracellular compartments
2016 Pirazzini, Marco; Tehran, Domenico Azarnia; Leka, Oneda; Zanetti, Giulia; Rossetto, Ornella; Montecucco, Cesare