PERUZZO, ROBERTA
PERUZZO, ROBERTA
Dipartimento di Biologia - DiBio
A novel mitochondrial kv1.3–caveolin axis controls cell survival and apoptosis
2021 Capera, J.; Perez-Verdaguer, M.; Peruzzo, R.; Navarro-Perez, M.; Martinez-Pinna, J.; Alberola-Die, A.; Morales, A.; Leanza, L.; Szabo, I.; Felipe, A.
Compensatory expression of NRF2-dependent antioxidant genes is required to overcome the lethal effects of Kv11.1 activation in breast cancer cells and PDOs
2021 Senyuk, V.; Eskandari, N.; Jiang, Y.; Garcia-Varela, R.; Sundstrom, R.; Leanza, L.; Peruzzo, R.; Burkard, M.; Minshall, R. D.; Gentile, S.
Contribution of mitochondrial ion channels to chemo-resistance in cancer cells
2019 Peruzzo, R.; Szabo, I.
Corrigendum to “Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family” [Redox Biol. 37 (2020 Sep 6) 101705–101721](S2213231720309101)(10.1016/j.redox.2020.101705)
2021 Peruzzo, R.; Mattarei, A.; Azzolini, M.; Becker-Flegler, K. A.; Romio, M.; Rigoni, G.; Carrer, A.; Biasutto, L.; Parrasia, S.; Kadow, S.; Manago, A.; Urbani, A.; Rossa, A.; Semenzato, G.; Soriano, M. E.; Trentin, L.; Ahmad, S.; Edwards, M.; Gulbins, E.; Paradisi, C.; Zoratti, M.; Leanza, L.; Szabo, I.
Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo
2017 Leanza, Luigi; Romio, Matteo; Becker, Katrin Anne; Azzolini, Michele; Trentin, Livio; Manago', Antonella; Venturini, Elisa; Zaccagnino, Angela; Mattarei, Andrea; Carraretto, Luca; Urbani, Andrea; Kadow, Stephanie; Biasutto, Lucia; Martini, Veronica; Severin, Filippo; Peruzzo, Roberta; Trimarco, Valentina; Egberts, Jan Hendrik; Hauser, Charlotte; Visentin, Andrea; Semenzato, GIANPIETRO CARLO; Kalthoff, Holger; Zoratti, Mario; Gulbins, Erich; Paradisi, Cristina; Szabo', Ildiko'
Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction
2021 Peruzzo, Roberta; Corrà, Samantha; Costa, Roberto; Brischigliaro, Michele; Varanita, Tatiana; Biasutto, Lucia; Rampazzo, Chiara; Ghezzi, Daniele; Leanza, Luigi; Zoratti, Mario; Zeviani, Massimo; De Pittà, Cristiano; Viscomi, Carlo; Costa, Rodolfo; Szabò, Ildikò
Impact of intracellular ion channels on cancer development and progression
2016 Peruzzo, Roberta; Biasutto, Lucia; Szabo', Ildiko'; Leanza, Luigi
Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction
2019 Costa, R.; Peruzzo, R.; Bachmann, M.; Monta, G. D.; Vicario, M.; Santinon, G.; Mattarei, A.; Moro, E.; Quintana-Cabrera, R.; Scorrano, L.; Zeviani, M.; Vallese, F.; Zoratti, M.; Paradisi, C.; Argenton, F.; Brini, M.; Cali, T.; Dupont, S.; Szabo, I.; Leanza, L.
Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family
2020 Peruzzo, Roberta; Mattarei, Andrea; Azzolini, Michele; Becker-Flegler, Katrin Anne; Romio, Matteo; Rigoni, Giovanni; Carrer, Andrea; Biasutto, Lucia; Parrasia, Sofia; Kadow, Stephanie; Managò, Antonella; Urbani, Andrea; Rossa, Andrea; Semenzato, Gianpietro; Soriano, Maria Eugenia; Trentin, Livio; Ahmad, Syed; Edwards, Michael; Gulbins, Erich; Paradisi, Cristina; Zoratti, Mario; Leanza, Luigi; Szabò, Ildikò
Mitochondrial apoptosis is induced by Alkoxy phenyl-1-propanone derivatives through PP2A-mediated dephosphorylation of Bad and Foxo3A in CLL
2019 Pagano, Mario Angelo; Tibaldi, Elena; Molino, Pierfrancesco; Frezzato, Federica; Trimarco, Valentina; Facco, Monica; Zagotto, Giuseppe; Ribaudo, Giovanni; Leanza, Luigi; Peruzzo, Roberta; Szabò, Ildikò; Visentin, Andrea; Frasson, Martina; Semenzato, Gianpietro; Trentin, Livio; Brunati, Anna Maria
Mitochondrial metabolism, contact sites and cellular calcium signaling: Implications for tumorigenesis
2020 Peruzzo, R.; Costa, R.; Bachmann, M.; Leanza, L.; Szabo, I.
Mitochondrial potassium channels in cell death
2018 Checchetto, Vanessa; Azzolini, Michele; Peruzzo, Roberta; Capitanio, Paola; Leanza, Luigi
Modulation of mitochondrial energy balance in health and disease
2019 Peruzzo, Roberta
Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo
2022 Bachmann, Magdalena; Rossa, Andrea; Varanita, Tatiana; Fioretti, Bernard; Biasutto, Lucia; Milenkovic, Stefan; Checchetto, Vanessa; Peruzzo, Roberta; Ahmad, Syed A; Patel, Sameer H; Lukowski, Robert; Edwards, Michael J; Ceccarelli, Matteo; Gulbins, Erich; Zoratti, Mario; Mattarei, Andrea; Szabo, Ildiko
Pterostilbene improves cognitive performance in aged rats: An in vivo study
2019 Spina, M. L.; Sansevero, G.; Biasutto, L.; Zoratti, M.; Peruzzo, R.; Berardi, N.; Sale, A.; Azzolini, M.
Regulation of Proliferation by a Mitochondrial Potassium Channel in Pancreatic Ductal Adenocarcinoma Cells
2017 Peruzzo, Roberta; Mattarei, Andrea; Romio, Matteo; Paradisi, Cristina; Zoratti, Mario; Szabò, Ildikò; Leanza, Luigi
Targeting Mitochondrial Ion Channels to Fight Cancer
2018 Bachmann, Magdalena; Costa, Roberto; Peruzzo, Roberta; Prosdocimi, Elena; Checchetto, Vanessa; Leanza, Luigi
The displacement of frataxin from the mitochondrial cristae correlates with abnormal respiratory supercomplexes formation and bioenergetic defects in cells of Friedreich ataxia patients.
2021 Doni, Davide; Rigoni, Giovanni; Palumbo, Elisa; Baschiera, Elisa; Peruzzo, Roberta; DE ROSA, Edith; Caicci, Federico; Passerini, Leonardo; Bettio, Daniela; Russo, Antonella; Ildiko, Szabò; SORIANO GARCIA - CUERVA, MARIA EUGENIA; Salviati, Leonardo; Costantini, Paola
Tumor-reducing effect of the clinically used drug clofazimine in a SCID mouse model of pancreatic ductal adenocarcinoma
2017 Zaccagnino, Angela; Manago', Antonella; Leanza, Luigi; Gontarewitz, Artur; Linder, Bernhard; Azzolini, Michele; Biasutto, Lucia; Zoratti, Mario; Peruzzo, Roberta; Legler, Karen; Trauzold, Anna; Kalthoff, Holger; Szabo', Ildiko'