COZZA, GIORGIO
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 7.564
EU - Europa 926
AS - Asia 590
SA - Sud America 6
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 2
AF - Africa 1
Totale 9.092
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 7.558
CN - Cina 486
IT - Italia 368
FI - Finlandia 156
DE - Germania 120
SE - Svezia 103
GB - Regno Unito 70
VN - Vietnam 63
UA - Ucraina 57
IE - Irlanda 13
IN - India 11
NL - Olanda 9
FR - Francia 8
PH - Filippine 7
CA - Canada 6
HK - Hong Kong 6
JP - Giappone 6
RU - Federazione Russa 6
SG - Singapore 4
AT - Austria 3
BR - Brasile 3
IR - Iran 3
BE - Belgio 2
CH - Svizzera 2
ES - Italia 2
EU - Europa 2
HR - Croazia 2
ID - Indonesia 2
NZ - Nuova Zelanda 2
PL - Polonia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AR - Argentina 1
BD - Bangladesh 1
CL - Cile 1
GR - Grecia 1
HU - Ungheria 1
KW - Kuwait 1
PE - Perù 1
PT - Portogallo 1
ZA - Sudafrica 1
Totale 9.092
Salva come PNG Salva come JPEG
Città #
Fairfield 1.288
Woodbridge 849
Houston 724
Ann Arbor 685
Ashburn 558
Chandler 524
Cambridge 490
Seattle 464
Wilmington 460
Jacksonville 252
Padova 140
Princeton 138
Beijing 127
San Diego 124
Des Moines 110
Helsinki 80
Medford 79
Nanjing 66
Dong Ket 63
Roxbury 51
Boardman 44
Guangzhou 35
Shenyang 28
Hebei 27
Jinan 23
Nanchang 20
Tianjin 15
Changsha 14
London 14
New York 14
Dublin 13
Jiaxing 12
Norwalk 12
Hangzhou 10
Kharkiv 10
Washington 10
Falls Church 9
Redwood City 9
Rome 9
Aprilia 8
Milan 8
Ogden 8
Zhengzhou 8
Hefei 7
Ningbo 7
Taizhou 7
Cagliari 6
Davao City 6
Haikou 6
Los Angeles 6
Shanghai 6
Comerio 5
Dearborn 5
Nürnberg 5
Redmond 5
Taiyuan 5
Hong Kong 4
Indiana 4
Kilburn 4
Kunming 4
Mestre 4
Munich 4
Palermo 4
Singapore 4
Tappahannock 4
Tokyo 4
Ancona 3
Auburn Hills 3
Borås 3
Catania 3
North York 3
Prescot 3
San Francisco 3
São Paulo 3
Toronto 3
Brussels 2
Central 2
Costa Mesa 2
Fontaniva 2
Fuzhou 2
Gandhinagar 2
Hanover 2
Islington 2
Lanzhou 2
Lissone 2
Medan 2
Mestrino 2
Napoli 2
Notaresco 2
Nuremberg 2
Paris 2
Shaoxing 2
Termoli 2
Tolentino 2
Venice 2
Verona 2
Vienna 2
Würzburg 2
Yellow Springs 2
Acton 1
Totale 7.824
Salva come PNG Salva come JPEG
Nome #
Stealth iron oxide nanoparticles for organotropic drug targeting 175
A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient tumours 160
ALK Kinase Domain Mutations in Primary Anaplastic Large Cell Lymphoma: Consequences on NPM-ALK Activity and Sensitivity to Tyrosine Kinase Inhibitors. 159
Inhibition of Protein Kinase CK2 by Flavonoids and Tyrphostins. A Structural Insight. 158
The Selectivity of CK2 Inhibitor Quinalizarin: A Reevaluation 149
Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2 149
Protein disulfide isomerase and glutathione are alternative substrates in the one Cys catalytic cycle of glutathione peroxidase 7 144
Insight into the mechanism of ferroptosis inhibition by ferrostatin-1 144
"Genuine" Casein Kinase: The False Sister of CK2 That Phosphorylates Secreted Proteins at S-X-E/pS Motifs 142
Design, validation and efficacy of bisubstrate inhibitors specifically affecting ecto-CK2 kinase activity 139
A novel glucosyltransferase from Catharanthus roseus cell suspensions 136
Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. 130
Exploiting the repertoire of CK2 inhibitors to target DYRK and PIM kinases 127
Pyrazoloquinazoline tricyclic system as novel scaffold to design new kinase CK2 inhibitors 125
Inhibition of protein kinase CK2 by condensed polyphenolic derivatives. An in vitro and in vivo study 124
A Comparison of Thiol Peroxidase Mechanisms 121
Lack of glutathione peroxidase-8 in the ER impacts on lipid composition of HeLa cells microsomal membranes 120
The acidophilic kinases PLK2 and PLK3: structure, substrate targeting and inhibition 119
Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacological potential 117
Understanding mammalian glutathione peroxidase 7 in the light of its homologs 117
Inactivation of the glutathione peroxidase GPx4 by the ferroptosis-inducing molecule RSL3 requires the adaptor protein 14-3-3 epsilon 117
Glutathione peroxidase 4-catalyzed reduction of lipid hydroperoxides in membranes: The polar head of membrane phospholipids binds the enzyme and addresses the fatty acid hydroperoxide group toward the redox center 115
Insight the mechanism of ferroptosis inhibition by ferrostatin-1 115
8-Hydroxynaphthalene-1,4-dione derivative as novel compound for glioma treatment 114
Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors 114
Fam20C is under the control of sphingolipid signaling in human cell lines 114
Benextramine and derivatives as novel human monoamine oxidases inhibitors: an integrated approach 114
A pathogenic role for cystic fibrosis transmembrane conductance regulator in celiac disease 111
Covalently bound DNA on naked iron oxide nanoparticles: Intelligent colloidal nano-vector for cell transfection 110
The lysine-specific demethylase 1 is a novel substrate of protein kinase CK2 109
Chimeric peptides as modulators of CK2-dependent signaling: Mechanism of action and off-target effects 109
Isoform specific phosphorylation of p53 by protein kinase CK1 106
Synthesis and properties of a selective inhibitor of homeodomain-interacting protein kinase 2 (HIPK2). 105
Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma 105
Protein Kinase CK2 Inhibitors: Emerging Anticancer Therapeutic Agents? 104
The selectivity of inhibitors of protein kinase CK2: an update 103
Biochemical and cellular mechanism of protein kinase CK2 inhibition by deceptive curcumin 101
Cystic fibrosis transmembrane regulator fragments with the Phe508 deletion exert a dual allosteric control over the master kinase CK2 100
Casein kinases as potential therapeutic targets 99
Structural features underlying the selectivity of the kinase inhibitors NBC and dNBC: role of a nitro group that discriminates between CK2 and DYRK1A 98
Hydrophobic Derivatives of Glycopeptide Antibiotics as Inhibitors of Protein Kinases 96
Elucidation of the ribonuclease a aggregation process mediated by 3D domain swapping: A computational approach reveals possible new multimeric structures. 95
Strategie computazionali per lo studio delle interazioni tra macromolecole e per la ricerca di nuovi inibitori di proteine chinasi 94
Investigation on PLK2 and PLK3 substrate recognition. 93
Tools to discriminate between targets of CK2 vs PLK2/PLK3 acidophilic kinases. 93
Protein kinase CK2 inhibitors: a patent review 93
Autophosphorylation at the regulatory beta subunit reflects the supramolecular organization of protein kinase CK2 90
The landscape of BRAF transcript and protein variants in human cancer 90
Pharmacophore-guided discovery of CDC25 inhibitors causing cell cycle arrest and tumor regression 89
Lipid peroxidation and GPx4: the players of the oxygen paradox 86
Urolithin as a converging scaffold linking ellagic acid and coumarin analogues: design of potent protein kinase CK2 inhibitors. 85
A new role for sphingosine: Up-regulation of Fam20C, the genuine casein kinase that phosphorylates secreted proteins 85
Detection of Phospho-Sites Generated by Protein Kinase CK2 in CFTR: Mechanistic Aspects of Thr1471 Phosphorylation 83
Novel and old polyamine analogues to target human monoamine oxidases and vascular adhesion protein-1 82
Medicinal chemistry and the molecular operating environment (MOE): application of QSAR and molecular docking to drug discovery 82
Missing GPx8 activity in ER impacts on lipid composition 81
Scouting Novel Protein Kinase A (PKA) Inhibitors by Using a Consensus Docking-Based Virtual Screening Approach 80
Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases 80
ATP Non-Competitive Ser/Thr Kinase Inhibitors as Potential Anticancer Agents 78
The Golgi ‘casein kinase’ Fam20C is a genuine ‘phosvitin kinase’ and phosphorylates polyserine stretches devoid of the canonical consensus 78
Glutathione peroxidase 4 77
Cystic fibrosis transmembrane regulator fragments with the Phe508 deletion exert a dual allosteric control over the master kinase CK2. 77
The Dark Side of Protein Kinase CK2 Inhibition 76
How Druggable Is Protein Kinase CK2? 75
Tetraiodobenzimidazoles are potent inhibitors of protein kinase CK2 73
Does CK2 start chromatin condensation in mitotic phase? 72
TG2 regulates the heat-shock response by the post-translational modification of HSF1 72
Kinase CK2 Inhibition: An Update 70
Unprecedented Selectivity and Structural Determinants of a New Class of Protein Kinase CK2 Inhibitors in Clinical Trials for the Treatment of Cancer 69
The development of CK2 inhibitors: From traditional pharmacology to in silico rational drug design 69
Regulatory subunit of protein kinase CK2 contributes to the recognition of the substrate consensus sequence. A study with an eIF2 beta-derived peptide 67
Development of a yeast-based system to identify new hBRAFV600E functional interactors 67
Identification of novel protein kinase CK1 delta (CK1 delta) inhibitors through structure-based virtual screening 66
Role of interaction and nucleoside diphosphate kinase b in regulation of the cystic fibrosis transmembrane conductance regulator function by camp-dependent protein kinase a 63
Glutathione Peroxidase-4 63
Coumarin as attractive casein kinase 2(CK2) inhibitor scaffold: an integrated approach to elucidate the putative binding motif and explain structure-activity relationship. 61
A novel splicing variant encoding putative catalytic alpha subunit of maize protein kinase CK2. 58
The catalytic mechanism of Glutathione Peroxidases 57
Subverted signalling by protein kinase CK2 in Delta F508 CFTR expressing cells 57
Aerobic pyruvate metabolism sensitizes cells to ferroptosis primed by GSH depletion 56
Benextramine derivatives as probes to target human monoamine oxidases 53
Inhibition of cell cycle and apoptosis in human cervix carcinoma cell lines induced by rhein, quercetin and plumbagin and in silico designed semi synthetic analogs 52
Identification of Snps and Indels mutation in ALK kinase domain by 454 massive parallel pyrosequencing 51
Biosensor based on aminoaldehyde dehydrogenase-iron nanoparticle complex for aminoaldehydes determination in spirits 51
DEVELOPMENT OF CK2 INHIBITORS FOR TARGETING DYRK AND PIM KINASES 51
The importance of negative determinants as modulators of CK2 targeting. The lesson of Akt2 S131 51
Mechanism of GSH Peroxidases III: GPx4 but not GPx1 binds to polar heads of phospholipids in membranes through a cationic area that also precisely addresses the hydroperoxide groups to the redox centre of the enzyme 49
8-HYDROXYNAPHTHALENE-1,4-DIONES NOVEL JUGLONE DERIVATIVES IN GLIOMA TREATMENT 48
Protein corona for proteome fingerprinting 47
Enzyme-iron nanoparticle direct interactions: hybrid formation and application for a coulometric biosensor for aminoaldehydes 47
An Iron Shield to Protect Epigallocatehin-3-Gallate from Degradation: Multifunctional Self-Assembled Iron Oxide Nanocarrier Enhances Protein Kinase CK2 Intracellular Targeting and Inhibition 47
Polyamine analogues and human amine oxidases: from a new substrate towards potential inhibitors. 46
Enzyme-iron nanoparticle direct interactions: complex formation and application for a coulometric biosensor for aminoaldehydes 45
Glutathione peroxidase 4, pp 223-234. In Selenium. Its Molecular Biology and Role in Human Health. 4th ed. 45
Role of carboxylic group pattern on protein surface in the recognition of iron oxide nanoparticles: A key for protein corona formation 45
Inhibition of cell cycle and apoptosis in human cervix carcinoma cell lines induced by rhein, quercetin and plumbagin and in silico designed semisynthetic analogs. 44
Regolazione dell'espressione e funzione di NPM-ALK nel Linfoma Anaplastico a Grandi Cellule: analisi mutazionale del complesso NPM-ALK/HSP90 ed implicazione sulla stabilità proteica 41
Natural and semisynthetic antraquinones, flavonoids and naphtoquinones effects on cell cycle in human ovarian cancer 40
Coulometric biosensor for aminoaldehydes based on the direct electro-oxidation of NADH on iron oxide nanoparticle modified electrode 39
Intracellular protein kinase CK2 inhibition by ferulic acid-based trimodal nanodevice 38
Totale 8.926
Salva come PNG Salva come JPEG
Categoria #
all - tutte 29.687
article - articoli 26.223
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 1.040
Totale 56.950
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019719 0 0 0 0 0 0 0 0 0 169 296 254
2019/20202.263 247 81 71 192 229 166 237 242 299 249 165 85
2020/20211.513 91 89 69 107 62 80 60 150 206 223 209 167
2021/20221.549 38 208 262 95 72 115 77 139 60 41 143 299
2022/20231.150 229 107 31 152 172 164 4 73 138 10 50 20
2023/2024573 36 110 79 54 75 58 58 51 28 24 0 0
Totale 9.240